Diacylglycerol O-Acyltransferase
"Diacylglycerol O-Acyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyses the last step of the TRIACYLGLYCEROL synthesis reaction in which diacylglycerol is covalently joined to LONG-CHAIN ACYL COA to form triglyceride. It was formerly categorized as EC 2.3.1.124.
| Descriptor ID |
D051048
|
| MeSH Number(s) |
D08.811.913.050.387
|
| Concept/Terms |
Diacylglycerol O-Acyltransferase- Diacylglycerol O-Acyltransferase
- Diacylglycerol O Acyltransferase
- O-Acyltransferase, Diacylglycerol
- DAGAT Enzyme
- Palmitoyl-Coenzyme A-sn-1,2-Diacylglycerol Acyltransferase
- A-sn-1,2-Diacylglycerol Acyltransferase, Palmitoyl-Coenzyme
- Acyltransferase, Palmitoyl-Coenzyme A-sn-1,2-Diacylglycerol
- Palmitoyl Coenzyme A sn 1,2 Diacylglycerol Acyltransferase
- Diacylglycerol O-Acyltransferase 1
- Diacylglycerol O Acyltransferase 1
- O-Acyltransferase 1, Diacylglycerol
- Diglyceride Acyltransferase
- Acyltransferase, Diglyceride
- Palmitoyl-CoA-sn-1,2-Diacylglycerol Acyltransferase
- Acyltransferase, Palmitoyl-CoA-sn-1,2-Diacylglycerol
- Palmitoyl CoA sn 1,2 Diacylglycerol Acyltransferase
- Acyl-Coenzyme A Diacyl-glycerol Acyltransferase
- Acyl Coenzyme A Diacyl glycerol Acyltransferase
- Diacylglycerol Acyltransferase
- Acyltransferase, Diacylglycerol
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Below are MeSH descriptors whose meaning is more general than "Diacylglycerol O-Acyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Diacylglycerol O-Acyltransferase".
This graph shows the total number of publications written about "Diacylglycerol O-Acyltransferase" by people in this website by year, and whether "Diacylglycerol O-Acyltransferase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Diacylglycerol O-Acyltransferase" by people in Profiles.
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Efficacy and safety of an orally administered DGAT2 inhibitor alone or coadministered with a liver-targeted ACC inhibitor in adults with non-alcoholic steatohepatitis (NASH): rationale and design of the phase II, dose-ranging, dose-finding, randomised, placebo-controlled MIRNA (Metabolic Interventions to Resolve NASH with fibrosis) study. BMJ Open. 2022 03 30; 12(3):e056159.
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Loss of ephrin B2 receptor (EPHB2) sets lipid rheostat by regulating proteins DGAT1 and ATGL inducing lipid droplet storage in prostate cancer cells. Lab Invest. 2021 07; 101(7):921-934.
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DGAT1 Inhibitor Suppresses Prostate Tumor Growth and Migration by Regulating Intracellular Lipids and Non-Centrosomal MTOC Protein GM130. Sci Rep. 2019 02 28; 9(1):3035.
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Knockdown of triglyceride synthesis does not enhance palmitate lipotoxicity or prevent oleate-mediated rescue in rat hepatocytes. Biochim Biophys Acta. 2016 09; 1861(9 Pt A):1005-1014.
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Developmental regulation of the catalytic subunit of the apolipoprotein B mRNA editing enzyme (APOBEC-1) in human small intestine. J Lipid Res. 1995 Aug; 36(8):1664-75.