"Hepatocyte Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Multifunctional growth factor which regulates both cell growth and cell motility. It exerts a strong mitogenic effect on hepatocytes and primary epithelial cells. Its receptor is PROTO-ONCOGENE PROTEINS C-MET.
| Descriptor ID |
D017228
|
| MeSH Number(s) |
D12.644.276.374.420 D12.776.467.374.420 D23.529.374.420
|
| Concept/Terms |
Hepatocyte Growth Factor- Hepatocyte Growth Factor
- Factor, Hepatocyte Growth
- Growth Factor, Hepatocyte
- Scatter Factor
- Factor, Scatter
- Hepatopoietin
- Hepatopoietin A
|
Below are MeSH descriptors whose meaning is more general than "Hepatocyte Growth Factor".
Below are MeSH descriptors whose meaning is more specific than "Hepatocyte Growth Factor".
This graph shows the total number of publications written about "Hepatocyte Growth Factor" by people in this website by year, and whether "Hepatocyte Growth Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1999 | 2 | 0 | 2 |
| 2001 | 0 | 2 | 2 |
| 2002 | 1 | 1 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 2 | 2 | 4 |
| 2005 | 1 | 1 | 2 |
| 2006 | 1 | 1 | 2 |
| 2007 | 6 | 2 | 8 |
| 2008 | 4 | 1 | 5 |
| 2009 | 2 | 0 | 2 |
| 2010 | 1 | 4 | 5 |
| 2011 | 2 | 4 | 6 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 2 | 3 |
| 2014 | 6 | 0 | 6 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hepatocyte Growth Factor" by people in Profiles.
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Dia1-dependent adhesions are required by epithelial tissues to initiate invasion. J Cell Biol. 2018 04 02; 217(4):1485-1502.
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MET in Lung Cancer: Biomarker Selection Based on Scientific Rationale. Mol Cancer Ther. 2017 04; 16(4):555-565.
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Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung Endothelium. J Biol Chem. 2016 12 30; 291(53):27187-27203.
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Asef mediates HGF protective effects against LPS-induced lung injury and endothelial barrier dysfunction. Am J Physiol Lung Cell Mol Physiol. 2015 Mar 01; 308(5):L452-63.
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PAX3 and ETS1 synergistically activate MET expression in melanoma cells. Oncogene. 2015 Sep 17; 34(38):4964-74.
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Asef controls vascular endothelial permeability and barrier recovery in the lung. Mol Biol Cell. 2015 Feb 15; 26(4):636-50.
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Hepatocyte growth factor-induced Asef-IQGAP1 complex controls cytoskeletal remodeling and endothelial barrier. J Biol Chem. 2015 Feb 13; 290(7):4097-109.
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Mutant MMP-9 and HGF gene transfer enhance resolution of CCl4-induced liver fibrosis in rats: role of ASH1 and EZH2 methyltransferases repression. PLoS One. 2014; 9(11):e112384.
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Microtubule dynamics control HGF-induced lung endothelial barrier enhancement. PLoS One. 2014; 9(9):e105912.
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Hepatocyte growth factor triggers distinct mechanisms of Asef and Tiam1 activation to induce endothelial barrier enhancement. Cell Signal. 2014 Nov; 26(11):2306-16.