"Interferons" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions.
| Descriptor ID |
D007372
|
| MeSH Number(s) |
D12.644.276.374.440 D12.776.467.374.440 D23.529.374.440
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Interferons".
Below are MeSH descriptors whose meaning is more specific than "Interferons".
This graph shows the total number of publications written about "Interferons" by people in this website by year, and whether "Interferons" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 1 | 1 | 2 |
| 2001 | 1 | 2 | 3 |
| 2002 | 1 | 2 | 3 |
| 2004 | 1 | 1 | 2 |
| 2007 | 1 | 2 | 3 |
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 5 | 6 |
| 2011 | 4 | 6 | 10 |
| 2012 | 3 | 2 | 5 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 3 | 4 |
| 2015 | 3 | 0 | 3 |
| 2016 | 1 | 1 | 2 |
| 2017 | 2 | 0 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 3 | 1 | 4 |
| 2022 | 3 | 4 | 7 |
| 2023 | 1 | 2 | 3 |
| 2024 | 1 | 1 | 2 |
| 2025 | 1 | 1 | 2 |
| 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Interferons" by people in Profiles.
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IFN-gene signatures in B cells following influenza A and B virus infection and influenza vaccination. EMBO Mol Med. 2026 04; 18(4):1456-1477.
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Trans-eQTL mapping prioritises USP18 as a negative regulator of interferon response at a lupus risk locus. Nat Commun. 2025 Oct 02; 16(1):8795.
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Macrophage peroxisomes guide alveolar regeneration and limit SARS-CoV-2 tissue sequelae. Science. 2025 03 07; 387(6738):eadq2509.
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Sustained IFN signaling is associated with delayed development of SARS-CoV-2-specific immunity. Nat Commun. 2024 May 16; 15(1):4177.
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Novel biomarkers and interferon signature in secondary progressive multiple sclerosis. J Neuroimmunol. 2024 04 15; 389:578328.
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Dissecting human population variation in single-cell responses to SARS-CoV-2. Nature. 2023 09; 621(7977):120-128.
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Human papillomavirus E5 suppresses immunity via inhibition of the immunoproteasome and STING pathway. Cell Rep. 2023 05 30; 42(5):112508.
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CAPRIN1 Is Required for Control of Viral Replication Complexes by Interferon Gamma. mBio. 2023 06 27; 14(3):e0017223.
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MACHETE identifies interferon-encompassing chromosome 9p21.3 deletions as mediators of immune evasion and metastasis. Nat Cancer. 2022 11; 3(11):1367-1385.
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Recent and future perspectives on engineering interferons and other cytokines as therapeutics. Trends Biochem Sci. 2023 03; 48(3):259-273.