"Interferons" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions.
| Descriptor ID |
D007372
|
| MeSH Number(s) |
D12.644.276.374.440 D12.776.467.374.440 D23.529.374.440
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Interferons".
Below are MeSH descriptors whose meaning is more specific than "Interferons".
This graph shows the total number of publications written about "Interferons" by people in this website by year, and whether "Interferons" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 2 | 3 |
| 1996 | 0 | 1 | 1 |
| 1998 | 1 | 1 | 2 |
| 2001 | 1 | 2 | 3 |
| 2002 | 2 | 2 | 4 |
| 2004 | 1 | 1 | 2 |
| 2007 | 1 | 2 | 3 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 5 | 6 |
| 2011 | 4 | 6 | 10 |
| 2012 | 3 | 2 | 5 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 3 | 4 |
| 2015 | 3 | 0 | 3 |
| 2016 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 2 | 1 | 3 |
| 2022 | 3 | 4 | 7 |
| 2023 | 1 | 0 | 1 |
| 2024 | 1 | 1 | 2 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interferons" by people in Profiles.
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Structural studies of the IFN?4 receptor complex using cryoEM enabled by protein engineering. Nat Commun. 2025 Jan 18; 16(1):818.
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Sustained IFN signaling is associated with delayed development of SARS-CoV-2-specific immunity. Nat Commun. 2024 May 16; 15(1):4177.
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Novel biomarkers and interferon signature in secondary progressive multiple sclerosis. J Neuroimmunol. 2024 04 15; 389:578328.
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CAPRIN1 Is Required for Control of Viral Replication Complexes by Interferon Gamma. mBio. 2023 06 27; 14(3):e0017223.
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MACHETE identifies interferon-encompassing chromosome 9p21.3 deletions as mediators of immune evasion and metastasis. Nat Cancer. 2022 11; 3(11):1367-1385.
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Recent and future perspectives on engineering interferons and other cytokines as therapeutics. Trends Biochem Sci. 2023 03; 48(3):259-273.
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SARS-CoV-2 Diverges from Other Betacoronaviruses in Only Partially Activating the IRE1a/XBP1 Endoplasmic Reticulum Stress Pathway in Human Lung-Derived Cells. mBio. 2022 10 26; 13(5):e0241522.
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A 2D Nanoradiosensitizer Enhances Radiotherapy and Delivers STING Agonists to Potentiate Cancer Immunotherapy. Adv Mater. 2022 Sep; 34(39):e2110588.
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RNA editing underlies genetic risk of common inflammatory diseases. Nature. 2022 08; 608(7923):569-577.
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Cannabidiol inhibits SARS-CoV-2 replication through induction of the host ER stress and innate immune responses. Sci Adv. 2022 Feb 25; 8(8):eabi6110.