Thienamycins
"Thienamycins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Beta-lactam antibiotics that differ from PENICILLINS in having the thiazolidine sulfur atom replaced by carbon, the sulfur then becoming the first atom in the side chain. They are unstable chemically, but have a very broad antibacterial spectrum. Thienamycin and its more stable derivatives are proposed for use in combinations with enzyme inhibitors.
| Descriptor ID |
D013845
|
| MeSH Number(s) |
D02.065.589.099.124.300 D04.075.080.875.099.221.124.300
|
| Concept/Terms |
Thienamycins- Thienamycins
- Antibiotics, Thienamycin
- Thienamycin Antibiotics
|
Below are MeSH descriptors whose meaning is more general than "Thienamycins".
Below are MeSH descriptors whose meaning is more specific than "Thienamycins".
This graph shows the total number of publications written about "Thienamycins" by people in this website by year, and whether "Thienamycins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1982 | 1 | 0 | 1 |
| 1984 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
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Below are the most recent publications written about "Thienamycins" by people in Profiles.
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Gavin PJ, Suseno MT, Cook FV, Peterson LR, Thomson RB. Left-sided endocarditis caused by Pseudomonas aeruginosa: successful treatment with meropenem and tobramycin. Diagn Microbiol Infect Dis. 2003 Oct; 47(2):427-30.
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Lerner SA, Dudek EJ, Boisvert WE, Berndt KD. Effect of highly potent antipseudomonal beta-lactam agents alone and in combination with aminoglycosides against Pseudomonas aeruginosa. Rev Infect Dis. 1984 Sep-Oct; 6 Suppl 3:S678-88.
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Dudek EJ, Stephenson JD, Bohnhoff M, Lerner SA. Susceptibility of Neisseria meningitidis and Neisseria gonorrhoeae isolates to N-formimidoyl thienamycin. Antimicrob Agents Chemother. 1982 Nov; 22(5):926-9.