Upstream Stimulatory Factors
"Upstream Stimulatory Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ubiquitously expressed basic HELIX-LOOP-HELIX MOTIF transcription factors. They bind CANNTG sequences in the promoters of a variety of GENES involved in carbohydrate and lipid metabolism.
| Descriptor ID |
D051720
|
| MeSH Number(s) |
D12.776.260.103.937 D12.776.930.125.937
|
| Concept/Terms |
Upstream Stimulatory Factors- Upstream Stimulatory Factors
- USF Transcription Factors
- Helix-Loop-Helix Activator USF
- Helix Loop Helix Activator USF
- USF, Helix-Loop-Helix Activator
|
Below are MeSH descriptors whose meaning is more general than "Upstream Stimulatory Factors".
Below are MeSH descriptors whose meaning is more specific than "Upstream Stimulatory Factors".
This graph shows the total number of publications written about "Upstream Stimulatory Factors" by people in this website by year, and whether "Upstream Stimulatory Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Upstream Stimulatory Factors" by people in Profiles.
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Upstream stimulatory factor 1 activates GATA5 expression through an E-box motif. Biochem J. 2012 Aug 15; 446(1):89-98.
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The linkage and association of the gene encoding upstream stimulatory factor 1 with type 2 diabetes and metabolic syndrome in the Chinese population. Diabetologia. 2005 Oct; 48(10):2018-24.
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USF-1 and USF-2 trans-repress IL-1beta-induced iNOS transcription in mesangial cells. Am J Physiol Cell Physiol. 2002 Oct; 283(4):C1065-72.