 Calcium Channels
"Calcium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorized as L-, T-, N-, P-, Q-, and R-types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. The L- and T-types are present throughout the cardiovascular and central nervous systems and the N-, P-, Q-, & R-types are located in neuronal tissue.
| Descriptor ID |
D015220
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| MeSH Number(s) |
D12.776.157.530.400.150 D12.776.543.550.425.150 D12.776.543.585.400.150
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| Concept/Terms |
Calcium Channels- Calcium Channels
- Ion Channel, Calcium
- Calcium Ion Channel
- Ion Channels, Calcium
- Calcium Ion Channels
- Calcium Channel Blocker Receptor
- VDCC
- Receptors, Calcium Channel Blocker
- Calcium Channel Antagonist Receptors
- Receptors, Calcium Channel Antagonist
- Calcium Channel Antagonist Receptor
- Voltage-Dependent Calcium Channels
- Calcium Channels, Voltage-Dependent
- Channels, Voltage-Dependent Calcium
- Voltage Dependent Calcium Channels
- Calcium Channel
- Calcium Channel Blocker Receptors
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Below are MeSH descriptors whose meaning is more general than "Calcium Channels".
Below are MeSH descriptors whose meaning is more specific than "Calcium Channels".
This graph shows the total number of publications written about "Calcium Channels" by people in this website by year, and whether "Calcium Channels" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 1 | 3 | 4 | | 1990 | 1 | 2 | 3 | | 1991 | 2 | 0 | 2 | | 1992 | 4 | 1 | 5 | | 1993 | 6 | 3 | 9 | | 1994 | 9 | 1 | 10 | | 1995 | 5 | 2 | 7 | | 1996 | 9 | 3 | 12 | | 1997 | 7 | 3 | 10 | | 1998 | 4 | 2 | 6 | | 1999 | 2 | 3 | 5 | | 2000 | 4 | 3 | 7 | | 2001 | 5 | 0 | 5 | | 2002 | 4 | 2 | 6 | | 2003 | 5 | 4 | 9 | | 2004 | 4 | 2 | 6 | | 2005 | 4 | 3 | 7 | | 2006 | 5 | 2 | 7 | | 2007 | 1 | 5 | 6 | | 2008 | 0 | 4 | 4 | | 2009 | 1 | 1 | 2 | | 2010 | 0 | 1 | 1 | | 2011 | 2 | 2 | 4 | | 2012 | 2 | 2 | 4 | | 2013 | 5 | 1 | 6 | | 2014 | 2 | 3 | 5 | | 2015 | 3 | 3 | 6 | | 2016 | 1 | 2 | 3 | | 2017 | 1 | 1 | 2 | | 2018 | 4 | 1 | 5 |
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Below are the most recent publications written about "Calcium Channels" by people in Profiles.
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Kintzer AF, Green EM, Dominik PK, Bridges M, Armache JP, Deneka D, Kim SS, Hubbell W, Kossiakoff AA, Cheng Y, Stroud RM. Structural basis for activation of voltage sensor domains in an ion channel TPC1. Proc Natl Acad Sci U S A. 2018 09 25; 115(39):E9095-E9104.
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Hulse RE, Li Z, Huang RK, Zhang J, Clapham DE. Cryo-EM structure of the polycystin 2-l1 ion channel. Elife. 2018 07 13; 7.
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Osinski BL, Kim A, Xiao W, Mehta NM, Kay LM. Pharmacological manipulation of the olfactory bulb modulates beta oscillations: testing model predictions. J Neurophysiol. 2018 09 01; 120(3):1090-1106.
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Pastor PDH, Du X, Fazal S, Davies AN, Gomez CM. Targeting the CACNA1A IRES as a Treatment for Spinocerebellar Ataxia Type 6. Cerebellum. 2018 02; 17(1):72-77.
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Du X, Gomez CM. Spinocerebellar [corrected] Ataxia Type 6: Molecular Mechanisms and Calcium Channel Genetics. Adv Exp Med Biol. 2018; 1049:147-173.
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Peng C, Li L, Zhang MD, Bengtsson Gonzales C, Parisien M, Belfer I, Usoskin D, Abdo H, Furlan A, Häring M, Lallemend F, Harkany T, Diatchenko L, Hökfelt T, Hjerling-Leffler J, Ernfors P. miR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes. Science. 2017 06 16; 356(6343):1168-1171.
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Hong Z, Chen KH, DasGupta A, Potus F, Dunham-Snary K, Bonnet S, Tian L, Fu J, Breuils-Bonnet S, Provencher S, Wu D, Mewburn J, Ormiston ML, Archer SL. MicroRNA-138 and MicroRNA-25 Down-regulate Mitochondrial Calcium Uniporter, Causing the Pulmonary Arterial Hypertension Cancer Phenotype. Am J Respir Crit Care Med. 2017 Feb 15; 195(4):515-529.
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Xie T, Appelbaum D, Bernard J, Padmanaban M, Pu Y, Gomez C. Evaluation of parkinsonism and striatal dopamine transporter loss in patients with spinocerebellar ataxia type 6. J Neurol. 2016 Nov; 263(11):2302-2307.
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Miyazaki Y, Du X, Muramatsu S, Gomez CM. An miRNA-mediated therapy for SCA6 blocks IRES-driven translation of the CACNA1A second cistron. Sci Transl Med. 2016 07 13; 8(347):347ra94.
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Osinski BL, Kay LM. Granule cell excitability regulates gamma and beta oscillations in a model of the olfactory bulb dendrodendritic microcircuit. J Neurophysiol. 2016 08 01; 116(2):522-39.
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