 HLA-A Antigens
"HLA-A Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Polymorphic class I human histocompatibility (HLA) surface antigens present on almost all nucleated cells. At least 20 antigens have been identified which are encoded by the A locus of multiple alleles on chromosome 6. They serve as targets for T-cell cytolytic responses and are involved with acceptance or rejection of tissue/organ grafts.
| Descriptor ID |
D015234
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| MeSH Number(s) |
D12.776.395.550.489.400 D12.776.543.550.421.400 D23.050.301.500.100.400 D23.050.301.500.450.370 D23.050.705.552.100.400 D23.050.705.552.450.370
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| Concept/Terms |
HLA-A Antigens- HLA-A Antigens
- HLA A Antigens
- HLA-A
- Antigens, HLA-A
- Antigens, HLA A
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Below are MeSH descriptors whose meaning is more general than "HLA-A Antigens".
Below are MeSH descriptors whose meaning is more specific than "HLA-A Antigens".
This graph shows the total number of publications written about "HLA-A Antigens" by people in this website by year, and whether "HLA-A Antigens" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1983 | 1 | 1 | 2 | | 1985 | 0 | 1 | 1 | | 1987 | 0 | 1 | 1 | | 1988 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1996 | 2 | 0 | 2 | | 1997 | 0 | 3 | 3 | | 2000 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2004 | 1 | 1 | 2 | | 2005 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 4 | 2 | 6 | | 2011 | 2 | 0 | 2 | | 2012 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2016 | 0 | 2 | 2 | | 2017 | 0 | 2 | 2 | | 2020 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "HLA-A Antigens" by people in Profiles.
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Carvajal RD, Nathan P, Sacco JJ, Orloff M, Hernandez-Aya LF, Yang J, Luke JJ, Butler MO, Stanhope S, Collins L, McAlpine C, Holland C, Abdullah SE, Sato T. Phase I Study of Safety, Tolerability, and Efficacy of Tebentafusp Using a Step-Up Dosing Regimen and Expansion in Patients With Metastatic Uveal Melanoma. J Clin Oncol. 2022 06 10; 40(17):1939-1948.
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Hikichi T, Sakamoto M, Harada M, Saito M, Yamane Y, Tokumura K, Nakamura Y. Identification of cytotoxic T cells and their T cell receptor sequences targeting COVID-19 using MHC class I-binding peptides. J Hum Genet. 2022 Jul; 67(7):411-419.
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Toyoshima Y, Nemoto K, Matsumoto S, Nakamura Y, Kiyotani K. SARS-CoV-2 genomic variations associated with mortality rate of COVID-19. J Hum Genet. 2020 Dec; 65(12):1075-1082.
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Gee MH, Han A, Lofgren SM, Beausang JF, Mendoza JL, Birnbaum ME, Bethune MT, Fischer S, Yang X, Gomez-Eerland R, Bingham DB, Sibener LV, Fernandes RA, Velasco A, Baltimore D, Schumacher TN, Khatri P, Quake SR, Davis MM, Garcia KC. Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes. Cell. 2018 01 25; 172(3):549-563.e16.
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Integrated genomic and molecular characterization of cervical cancer. Nature. 2017 03 16; 543(7645):378-384.
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Spranger S, Luke JJ, Bao R, Zha Y, Hernandez KM, Li Y, Gajewski AP, Andrade J, Gajewski TF. Density of immunogenic antigens does not explain the presence or absence of the T-cell-inflamed tumor microenvironment in melanoma. Proc Natl Acad Sci U S A. 2016 11 29; 113(48):E7759-E7768.
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El Bissati K, Chentoufi AA, Krishack PA, Zhou Y, Woods S, Dubey JP, Vang L, Lykins J, Broderick KE, Mui E, Suzuki Y, Sa Q, Bi S, Cardona N, Verma SK, Fraczek L, Reardon CA, Sidney J, Alexander J, Sette A, Vedvick T, Fox C, Guderian JA, Reed S, Roberts CW, McLeod R. Adjuvanted multi-epitope vaccines protect HLA-A*11:01 transgenic mice against Toxoplasma gondii. JCI Insight. 2016 09 22; 1(15):e85955.
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Chin YM, Mushiroda T, Takahashi A, Kubo M, Krishnan G, Yap LF, Teo SH, Lim PV, Yap YY, Pua KC, Kamatani N, Nakamura Y, Sam CK, Khoo AS. HLA-A SNPs and amino acid variants are associated with nasopharyngeal carcinoma in Malaysian Chinese. Int J Cancer. 2015 Feb 01; 136(3):678-87.
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Aoki M, Hosono N, Takata S, Nakamura Y, Kamatani N, Kubo M. New pharmacogenetic test for detecting an HLA-A*31: 01 allele using the InvaderPlus assay. Pharmacogenet Genomics. 2012 Jun; 22(6):441-6.
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Tomita Y, Imai K, Senju S, Irie A, Inoue M, Hayashida Y, Shiraishi K, Mori T, Daigo Y, Tsunoda T, Ito T, Nomori H, Nakamura Y, Kohrogi H, Nishimura Y. A novel tumor-associated antigen, cell division cycle 45-like can induce cytotoxic T-lymphocytes reactive to tumor cells. Cancer Sci. 2011 Apr; 102(4):697-705.
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