"HLA-B Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Class I human histocompatibility (HLA) surface antigens encoded by more than 30 detectable alleles on locus B of the HLA complex, the most polymorphic of all the HLA specificities. Several of these antigens (e.g., HLA-B27, -B7, -B8) are strongly associated with predisposition to rheumatoid and other autoimmune disorders. Like other class I HLA determinants, they are involved in the cellular immune reactivity of cytolytic T lymphocytes.
Descriptor ID |
D015235
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MeSH Number(s) |
D12.776.395.550.489.500 D12.776.543.550.439.500 D23.050.301.500.100.500 D23.050.301.500.450.380 D23.050.705.552.100.500 D23.050.705.552.450.380
|
Concept/Terms |
HLA-B Antigens- HLA-B Antigens
- HLA B Antigens
- HLA-B
- Antigens, HLA-B
- Antigens, HLA B
|
Below are MeSH descriptors whose meaning is more general than "HLA-B Antigens".
Below are MeSH descriptors whose meaning is more specific than "HLA-B Antigens".
This graph shows the total number of publications written about "HLA-B Antigens" by people in this website by year, and whether "HLA-B Antigens" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 0 | 1 |
1995 | 1 | 1 | 2 |
1996 | 2 | 0 | 2 |
1997 | 1 | 1 | 2 |
2000 | 1 | 0 | 1 |
2001 | 4 | 0 | 4 |
2006 | 1 | 0 | 1 |
2009 | 1 | 0 | 1 |
2010 | 2 | 2 | 4 |
2014 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "HLA-B Antigens" by people in Profiles.
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SARS-CoV-2 genomic variations associated with mortality rate of COVID-19. J Hum Genet. 2020 Dec; 65(12):1075-1082.
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Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller. Sci Transl Med. 2017 01 18; 9(373).
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Distinct activation phenotype of a highly conserved novel HLA-B57-restricted epitope during dengue virus infection. Immunology. 2014 Jan; 141(1):27-38.
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Development of new HLA-B*3505 genotyping method using Invader assay. Pharmacogenet Genomics. 2010 Oct; 20(10):630-3.
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HLA-C antigen mismatch is associated with worse outcome in unrelated donor peripheral blood stem cell transplantation. Biol Blood Marrow Transplant. 2011 Jun; 17(6):885-92.
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Identification of T. gondii epitopes, adjuvants, and host genetic factors that influence protection of mice and humans. Vaccine. 2010 May 21; 28(23):3977-89.
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Association between HLA-B*4001 and lipodystrophy among HIV-infected patients from Thailand who received a stavudine-containing antiretroviral regimen. Clin Infect Dis. 2010 Feb 15; 50(4):597-604.
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Assembly and intracellular trafficking of HLA-B*3501 and HLA-B*3503. Immunogenetics. 2009 Dec; 61(11-12):703-16.
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HLA-B*3505 allele is a strong predictor for nevirapine-induced skin adverse drug reactions in HIV-infected Thai patients. Pharmacogenet Genomics. 2009 Feb; 19(2):139-46.
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HLA-B44 polymorphisms at position 116 of the heavy chain influence TAP complex binding via an effect on peptide occupancy. J Immunol. 2006 Sep 01; 177(5):3150-61.