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Susan Sam

TitleAssociate Professor
InstitutionUniversity of Chicago
DepartmentMedicine-Endocrinology
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Utzschneider KM, Ehrmann DA, Arslanian SA, Barengolts E, Buchanan TA, Caprio S, Edelstein SL, Hannon TS, Kahn SE, Kozedub A, Mather KJ, Nadeau KJ, Sam S, Tripputi M, Xiang AH, El Ghormli L, RISE Consortium. Weight loss and ?-cell responses following gastric banding or pharmacotherapy in adults with impaired glucose tolerance or type 2 diabetes: a randomized trial. Obesity (Silver Spring). 2022 08; 30(8):1579-1588. PMID: 35894078.
      Citations:    Fields:    Translation:Humans
    2. Jiang C, Cifu AS, Sam S. Obesity and Weight Management for Prevention and Treatment of Type 2 Diabetes. JAMA. 2022 07 26; 328(4):389-390. PMID: 35816353.
      Citations:    Fields:    Translation:Humans
    3. Sam S, Edelstein SL, Arslanian SA, Barengolts E, Buchanan TA, Caprio S, Ehrmann DA, Hannon TS, Tjaden AH, Kahn SE, Mather KJ, Tripputi M, Utzschneider KM, Xiang AH, Nadeau KJ, RISE Consortium, RISE Consortium Investigators. Baseline Predictors of Glycemic Worsening in Youth and Adults With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes in the Restoring Insulin Secretion (RISE) Study. Diabetes Care. 2021 09; 44(9):1938-1947. PMID: 34131048; PMCID: PMC8740917.
      Citations: 7     Fields:    Translation:Humans
    4. Mokhlesi B, Tjaden AH, Temple KA, Edelstein SL, Sam S, Nadeau KJ, Hannon TS, Manchanda S, Mather KJ, Kahn SE, Ehrmann DA, Van Cauter E, RISE Consortium. Obstructive Sleep Apnea, Glucose Tolerance, and ?-Cell Function in Adults With Prediabetes or Untreated Type 2 Diabetes in the Restoring Insulin Secretion (RISE) Study. Diabetes Care. 2021 04; 44(4):993-1001. PMID: 33547205; PMCID: PMC7985427.
      Citations: 7     Fields:    Translation:Humans
    5. Sam S, Tasali E. Role of obstructive sleep apnea in metabolic risk in PCOS. Curr Opin Endocr Metab Res. 2021 Apr; 17:46-51. PMID: 34368492; PMCID: PMC8341449.
      Citations: 1     
    6. Mokhlesi B, Temple KA, Tjaden AH, Edelstein SL, Nadeau KJ, Hannon TS, Manchanda S, Sam S, Barengolts E, Utzschneider KM, Ehrmann DA, Van Cauter E, RISE Consortium. The association of sleep disturbances with glycemia and obesity in youth at risk for or with recently diagnosed type 2 diabetes. Pediatr Diabetes. 2019 12; 20(8):1056-1063. PMID: 31486162; PMCID: PMC7199716.
      Citations: 4     Fields:    Translation:Humans
    7. Sam S, Ehrmann DA. Pathogenesis and Consequences of Disordered Sleep in PCOS. Clin Med Insights Reprod Health. 2019; 13:1179558119871269. PMID: 31516314; PMCID: PMC6724486.
      Citations: 11     
    8. Mokhlesi B, Temple KA, Tjaden AH, Edelstein SL, Utzschneider KM, Nadeau KJ, Hannon TS, Sam S, Barengolts E, Manchanda S, Ehrmann DA, Van Cauter E, RISE Consortium. Association of Self-Reported Sleep and Circadian Measures With Glycemia in Adults With Prediabetes or Recently Diagnosed Untreated Type 2 Diabetes. Diabetes Care. 2019 07; 42(7):1326-1332. PMID: 31048411; PMCID: PMC6609965.
      Citations: 21     Fields:    Translation:Humans
    9. Casimiro I, Sam S, Brady MJ. Endocrine implications of bariatric surgery: a review on the intersection between incretins, bone, and sex hormones. Physiol Rep. 2019 05; 7(10):e14111. PMID: 31134746; PMCID: PMC6536581.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    10. Sam S. Differential effect of subcutaneous abdominal and visceral adipose tissue on cardiometabolic risk. Horm Mol Biol Clin Investig. 2018 Mar 09; 33(1). PMID: 29522417.
      Citations: 31     Fields:    Translation:HumansAnimals
    11. Sam S, Ehrmann DA. Metformin therapy for the reproductive and metabolic consequences of polycystic ovary syndrome. Diabetologia. 2017 09; 60(9):1656-1661. PMID: 28770330.
      Citations: 22     Fields:    Translation:Humans
    12. Sam S, Vellanki P, Yalamanchi SK, Bergman RN, Dunaif A. Exaggerated glucagon responses to hypoglycemia in women with polycystic ovary syndrome. Metabolism. 2017 06; 71:125-131. PMID: 28521865; PMCID: PMC5468004.
      Citations: 3     Fields:    Translation:Humans
    13. Mokhlesi B, Sam S, Ehrmann DA. Obstructive sleep apnea and polycystic ovary syndrome: cause or association? Sleep Med. 2017 08; 36:170-171. PMID: 28238552.
      Citations:    Fields:    Translation:Humans
    14. Sam S, Ehrmann DA. Hormonal Evaluation of Hyperandrogenism in Women. JAMA. 2015 Dec 15; 314(23):2557-8. PMID: 26670974.
      Citations: 1     Fields:    Translation:Humans
    15. Sam S, Scoccia B, Yalamanchi S, Mazzone T. Metabolic dysfunction in obese Hispanic women with polycystic ovary syndrome. Hum Reprod. 2015 Jun; 30(6):1358-64. PMID: 25857311; PMCID: PMC4498223.
      Citations: 2     Fields:    Translation:Humans
    16. Sam S. Adiposity and metabolic dysfunction in polycystic ovary syndrome. Horm Mol Biol Clin Investig. 2015 Feb; 21(2):107-16. PMID: 25781555.
      Citations: 9     Fields:    Translation:HumansCells
    17. Sam S, Mazzone T. Adipose tissue changes in obesity and the impact on metabolic function. Transl Res. 2014 Oct; 164(4):284-92. PMID: 24929206.
      Citations: 36     Fields:    Translation:Humans
    18. Huang ZH, Manickam B, Ryvkin V, Zhou XJ, Fantuzzi G, Mazzone T, Sam S. PCOS is associated with increased CD11c expression and crown-like structures in adipose tissue and increased central abdominal fat depots independent of obesity. J Clin Endocrinol Metab. 2013 Jan; 98(1):E17-24. PMID: 23118428; PMCID: PMC3537096.
      Citations: 30     Fields:    Translation:HumansCells
    19. Yalamanchi SK, Sam S, Cardenas MO, Holaday LW, Urbanek M, Dunaif A. Association of fibrillin-3 and transcription factor-7-like 2 gene variants with metabolic phenotypes in PCOS. Obesity (Silver Spring). 2012 Jun; 20(6):1273-8. PMID: 22301903; PMCID: PMC3346885.
      Citations: 8     Fields:    Translation:Humans
    20. Mokhlesi B, Scoccia B, Mazzone T, Sam S. Risk of obstructive sleep apnea in obese and nonobese women with polycystic ovary syndrome and healthy reproductively normal women. Fertil Steril. 2012 Mar; 97(3):786-91. PMID: 22264851; PMCID: PMC3292664.
      Citations: 12     Fields:    Translation:Humans
    21. Sam S, Haffner S, Davidson MH, D'Agostino R, Perez A, Mazzone T. Pioglitazone-mediated changes in lipoprotein particle composition are predicted by changes in adiponectin level in type 2 diabetes. J Clin Endocrinol Metab. 2012 Jan; 97(1):E110-4. PMID: 22072742; PMCID: PMC3412262.
      Citations: 6     Fields:    Translation:Humans
    22. Sidhwani S, Scoccia B, Sunghay S, Stephens-Archer CN, Mazzone T, Sam S. Polycystic ovary syndrome is associated with atherogenic changes in lipoprotein particle number and size independent of body weight. Clin Endocrinol (Oxf). 2011 Jul; 75(1):76-82. PMID: 21521284; PMCID: PMC3146971.
      Citations: 12     Fields:    Translation:Humans
    23. Zhao Y, Guo C, Hwang D, Lin B, Dingeldein M, Mihailescu D, Sam S, Sidhwani S, Zhang Y, Jain S, Skidgel RA, Prabhakar BS, Mazzone T, Holterman MJ. Selective destruction of mouse islet beta cells by human T lymphocytes in a newly-established humanized type 1 diabetic model. Biochem Biophys Res Commun. 2010 Sep 03; 399(4):629-36. PMID: 20691153.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    24. Coviello AD, Sam S, Legro RS, Dunaif A. High prevalence of metabolic syndrome in first-degree male relatives of women with polycystic ovary syndrome is related to high rates of obesity. J Clin Endocrinol Metab. 2009 Nov; 94(11):4361-6. PMID: 19837913; PMCID: PMC2775643.
      Citations: 31     Fields:    Translation:Humans
    25. Sam S, Haffner S, Davidson MH, D'Agostino RB, Feinstein S, Kondos G, Perez A, Mazzone T. Hypertriglyceridemic waist phenotype predicts increased visceral fat in subjects with type 2 diabetes. Diabetes Care. 2009 Oct; 32(10):1916-20. PMID: 19592623; PMCID: PMC2752928.
      Citations: 66     Fields:    Translation:Humans
    26. Sam S, Haffner S, Davidson MH, D'Agostino RB, Feinstein S, Kondos G, Perez A, Mazzone T. Relation of abdominal fat depots to systemic markers of inflammation in type 2 diabetes. Diabetes Care. 2009 May; 32(5):932-7. PMID: 19228869; PMCID: PMC2671130.
      Citations: 44     Fields:    Translation:Humans
    27. Sam S, Haffner S, Davidson MH, D'Agostino RB, Feinstein S, Kondos G, Perez A, Mazzone T. Relationship of abdominal visceral and subcutaneous adipose tissue with lipoprotein particle number and size in type 2 diabetes. Diabetes. 2008 Aug; 57(8):2022-7. PMID: 18469202; PMCID: PMC2494673.
      Citations: 43     Fields:    Translation:Humans
    28. Sam S, Coviello AD, Sung YA, Legro RS, Dunaif A. Metabolic phenotype in the brothers of women with polycystic ovary syndrome. Diabetes Care. 2008 Jun; 31(6):1237-41. PMID: 18332151; PMCID: PMC2897239.
      Citations: 24     Fields:    Translation:Humans
    29. Sam S, Frohman LA. Normal physiology of hypothalamic pituitary regulation. Endocrinol Metab Clin North Am. 2008 Mar; 37(1):1-22, vii. PMID: 18226728.
      Citations: 20     Fields:    Translation:Humans
    30. Sam S, Sung YA, Legro RS, Dunaif A. Evidence for pancreatic beta-cell dysfunction in brothers of women with polycystic ovary syndrome. Metabolism. 2008 Jan; 57(1):84-9. PMID: 18078863; PMCID: PMC2710887.
      Citations: 25     Fields:    Translation:HumansCells
    31. Urbanek M, Sam S, Legro RS, Dunaif A. Identification of a polycystic ovary syndrome susceptibility variant in fibrillin-3 and association with a metabolic phenotype. J Clin Endocrinol Metab. 2007 Nov; 92(11):4191-8. PMID: 17785364.
      Citations: 53     Fields:    Translation:HumansCells
    32. Sam S. Obesity and Polycystic Ovary Syndrome. Obes Manag. 2007 Apr; 3(2):69-73. PMID: 20436797; PMCID: PMC2861983.
      Citations: 63     
    33. Sam S, Legro RS, Essah PA, Apridonidze T, Dunaif A. Evidence for metabolic and reproductive phenotypes in mothers of women with polycystic ovary syndrome. Proc Natl Acad Sci U S A. 2006 May 02; 103(18):7030-5. PMID: 16632599; PMCID: PMC1459013.
      Citations: 44     Fields:    Translation:Humans
    34. Mattsson C, Stanhope CR, Sam S, Young WF. Image in endocrinology: testosterone-secreting ovarian tumor localized with (fluorine-18)-2-deoxyglucose positron emission tomography. J Clin Endocrinol Metab. 2006 Mar; 91(3):738-9. PMID: 16522702.
      Citations: 4     Fields:    Translation:Humans
    35. Sam S, Legro RS, Bentley-Lewis R, Dunaif A. Dyslipidemia and metabolic syndrome in the sisters of women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2005 Aug; 90(8):4797-802. PMID: 15899949; PMCID: PMC4428585.
      Citations: 35     Fields:    Translation:Humans
    36. Sam S, Molitch ME. The pituitary mass: diagnosis and management. Rev Endocr Metab Disord. 2005 Jan; 6(1):55-62. PMID: 15711915.
      Citations: 9     Fields:    Translation:Humans
    37. Sam S, Corbridge TC, Mokhlesi B, Comellas AP, Molitch ME. Cortisol levels and mortality in severe sepsis. Clin Endocrinol (Oxf). 2004 Jan; 60(1):29-35. PMID: 14678284.
      Citations: 31     Fields:    Translation:Humans
    38. Sam S, Dunaif A. Polycystic ovary syndrome: syndrome XX? Trends Endocrinol Metab. 2003 Oct; 14(8):365-70. PMID: 14516934.
      Citations: 75     Fields:    Translation:HumansCells
    39. Sam S, Molitch ME. Timing and special concerns regarding endocrine surgery during pregnancy. Endocrinol Metab Clin North Am. 2003 Jun; 32(2):337-54. PMID: 12800535.
      Citations: 12     Fields:    Translation:Humans
    40. Kamradt MC, Chen F, Sam S, Cryns VL. The small heat shock protein alpha B-crystallin negatively regulates apoptosis during myogenic differentiation by inhibiting caspase-3 activation. J Biol Chem. 2002 Oct 11; 277(41):38731-6. PMID: 12140279.
      Citations: 101     Fields:    Translation:HumansAnimalsCells
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