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Susan Sam

TitleAssociate Professor
InstitutionUniversity of Chicago
DepartmentMedicine-Endocrinology
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Mokhlesi B, Tjaden AH, Temple KA, Edelstein SL, Sam S, Nadeau KJ, Hannon TS, Manchanda S, Mather KJ, Kahn SE, Ehrmann DA, Van Cauter E. Obstructive Sleep Apnea, Glucose Tolerance, and ß-Cell Function in Adults With Prediabetes or Untreated Type 2 Diabetes in the Restoring Insulin Secretion (RISE) Study. Diabetes Care. 2021 Apr; 44(4):993-1001. PMID: 33547205.
      View in: PubMed
    2. Mokhlesi B, Temple KA, Tjaden AH, Edelstein SL, Nadeau KJ, Hannon TS, Manchanda S, Sam S, Barengolts E, Utzschneider KM, Ehrmann DA, Van Cauter E. The association of sleep disturbances with glycemia and obesity in youth at risk for or with recently diagnosed type 2 diabetes. Pediatr Diabetes. 2019 12; 20(8):1056-1063. PMID: 31486162.
      View in: PubMed
    3. Sam S, Ehrmann DA. Pathogenesis and Consequences of Disordered Sleep in PCOS. Clin Med Insights Reprod Health. 2019; 13:1179558119871269. PMID: 31516314.
      View in: PubMed
    4. Mokhlesi B, Temple KA, Tjaden AH, Edelstein SL, Utzschneider KM, Nadeau KJ, Hannon TS, Sam S, Barengolts E, Manchanda S, Ehrmann DA, Van Cauter E. Association of Self-Reported Sleep and Circadian Measures With Glycemia in Adults With Prediabetes or Recently Diagnosed Untreated Type 2 Diabetes. Diabetes Care. 2019 07; 42(7):1326-1332. PMID: 31048411.
      View in: PubMed
    5. Casimiro I, Sam S, Brady MJ. Endocrine implications of bariatric surgery: a review on the intersection between incretins, bone, and sex hormones. Physiol Rep. 2019 05; 7(10):e14111. PMID: 31134746.
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    6. Sam S. Differential effect of subcutaneous abdominal and visceral adipose tissue on cardiometabolic risk. Horm Mol Biol Clin Investig. 2018 Mar 09; 33(1). PMID: 29522417.
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    7. Sam S, Ehrmann DA. Metformin therapy for the reproductive and metabolic consequences of polycystic ovary syndrome. Diabetologia. 2017 09; 60(9):1656-1661. PMID: 28770330.
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    8. Sam S, Vellanki P, Yalamanchi SK, Bergman RN, Dunaif A. Exaggerated glucagon responses to hypoglycemia in women with polycystic ovary syndrome. Metabolism. 2017 06; 71:125-131. PMID: 28521865.
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    9. Mokhlesi B, Sam S, Ehrmann DA. Obstructive sleep apnea and polycystic ovary syndrome: cause or association? Sleep Med. 2017 08; 36:170-171. PMID: 28238552.
      View in: PubMed
    10. Sam S, Ehrmann DA. Hormonal Evaluation of Hyperandrogenism in Women. JAMA. 2015 Dec 15; 314(23):2557-8. PMID: 26670974.
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    11. Sam S, Scoccia B, Yalamanchi S, Mazzone T. Metabolic dysfunction in obese Hispanic women with polycystic ovary syndrome. Hum Reprod. 2015 Jun; 30(6):1358-64. PMID: 25857311.
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    12. Sam S. Adiposity and metabolic dysfunction in polycystic ovary syndrome. Horm Mol Biol Clin Investig. 2015 Feb; 21(2):107-16. PMID: 25781555.
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    13. Sam S, Mazzone T. Adipose tissue changes in obesity and the impact on metabolic function. Transl Res. 2014 Oct; 164(4):284-92. PMID: 24929206.
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    14. Huang ZH, Manickam B, Ryvkin V, Zhou XJ, Fantuzzi G, Mazzone T, Sam S. PCOS is associated with increased CD11c expression and crown-like structures in adipose tissue and increased central abdominal fat depots independent of obesity. J Clin Endocrinol Metab. 2013 Jan; 98(1):E17-24. PMID: 23118428.
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    15. Yalamanchi SK, Sam S, Cardenas MO, Holaday LW, Urbanek M, Dunaif A. Association of fibrillin-3 and transcription factor-7-like 2 gene variants with metabolic phenotypes in PCOS. Obesity (Silver Spring). 2012 Jun; 20(6):1273-8. PMID: 22301903.
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    16. Mokhlesi B, Scoccia B, Mazzone T, Sam S. Risk of obstructive sleep apnea in obese and nonobese women with polycystic ovary syndrome and healthy reproductively normal women. Fertil Steril. 2012 Mar; 97(3):786-91. PMID: 22264851.
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    17. Sam S, Haffner S, Davidson MH, D'Agostino R, Perez A, Mazzone T. Pioglitazone-mediated changes in lipoprotein particle composition are predicted by changes in adiponectin level in type 2 diabetes. J Clin Endocrinol Metab. 2012 Jan; 97(1):E110-4. PMID: 22072742.
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    18. Sidhwani S, Scoccia B, Sunghay S, Stephens-Archer CN, Mazzone T, Sam S. Polycystic ovary syndrome is associated with atherogenic changes in lipoprotein particle number and size independent of body weight. Clin Endocrinol (Oxf). 2011 Jul; 75(1):76-82. PMID: 21521284.
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    19. Zhao Y, Guo C, Hwang D, Lin B, Dingeldein M, Mihailescu D, Sam S, Sidhwani S, Zhang Y, Jain S, Skidgel RA, Prabhakar BS, Mazzone T, Holterman MJ. Selective destruction of mouse islet beta cells by human T lymphocytes in a newly-established humanized type 1 diabetic model. Biochem Biophys Res Commun. 2010 Sep 03; 399(4):629-36. PMID: 20691153.
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    20. Coviello AD, Sam S, Legro RS, Dunaif A. High prevalence of metabolic syndrome in first-degree male relatives of women with polycystic ovary syndrome is related to high rates of obesity. J Clin Endocrinol Metab. 2009 Nov; 94(11):4361-6. PMID: 19837913.
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    21. Sam S, Haffner S, Davidson MH, D'Agostino RB, Feinstein S, Kondos G, Perez A, Mazzone T. Hypertriglyceridemic waist phenotype predicts increased visceral fat in subjects with type 2 diabetes. Diabetes Care. 2009 Oct; 32(10):1916-20. PMID: 19592623.
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    22. Sam S, Haffner S, Davidson MH, D'Agostino RB, Feinstein S, Kondos G, Perez A, Mazzone T. Relation of abdominal fat depots to systemic markers of inflammation in type 2 diabetes. Diabetes Care. 2009 May; 32(5):932-7. PMID: 19228869.
      View in: PubMed
    23. Sam S, Haffner S, Davidson MH, D'Agostino RB, Feinstein S, Kondos G, Perez A, Mazzone T. Relationship of abdominal visceral and subcutaneous adipose tissue with lipoprotein particle number and size in type 2 diabetes. Diabetes. 2008 Aug; 57(8):2022-7. PMID: 18469202.
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    24. Sam S, Coviello AD, Sung YA, Legro RS, Dunaif A. Metabolic phenotype in the brothers of women with polycystic ovary syndrome. Diabetes Care. 2008 Jun; 31(6):1237-41. PMID: 18332151.
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    25. Sam S, Frohman LA. Normal physiology of hypothalamic pituitary regulation. Endocrinol Metab Clin North Am. 2008 Mar; 37(1):1-22, vii. PMID: 18226728.
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    26. Sam S, Sung YA, Legro RS, Dunaif A. Evidence for pancreatic beta-cell dysfunction in brothers of women with polycystic ovary syndrome. Metabolism. 2008 Jan; 57(1):84-9. PMID: 18078863.
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    27. Urbanek M, Sam S, Legro RS, Dunaif A. Identification of a polycystic ovary syndrome susceptibility variant in fibrillin-3 and association with a metabolic phenotype. J Clin Endocrinol Metab. 2007 Nov; 92(11):4191-8. PMID: 17785364.
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    28. Sam S. Obesity and Polycystic Ovary Syndrome. Obes Manag. 2007 Apr; 3(2):69-73. PMID: 20436797.
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    29. Sam S, Legro RS, Essah PA, Apridonidze T, Dunaif A. Evidence for metabolic and reproductive phenotypes in mothers of women with polycystic ovary syndrome. Proc Natl Acad Sci U S A. 2006 May 02; 103(18):7030-5. PMID: 16632599.
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    30. Mattsson C, Stanhope CR, Sam S, Young WF. Image in endocrinology: testosterone-secreting ovarian tumor localized with (fluorine-18)-2-deoxyglucose positron emission tomography. J Clin Endocrinol Metab. 2006 Mar; 91(3):738-9. PMID: 16522702.
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    31. Sam S, Legro RS, Bentley-Lewis R, Dunaif A. Dyslipidemia and metabolic syndrome in the sisters of women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2005 Aug; 90(8):4797-802. PMID: 15899949.
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    32. Sam S, Molitch ME. The pituitary mass: diagnosis and management. Rev Endocr Metab Disord. 2005 Jan; 6(1):55-62. PMID: 15711915.
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    33. Sam S, Corbridge TC, Mokhlesi B, Comellas AP, Molitch ME. Cortisol levels and mortality in severe sepsis. Clin Endocrinol (Oxf). 2004 Jan; 60(1):29-35. PMID: 14678284.
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    34. Sam S, Dunaif A. Polycystic ovary syndrome: syndrome XX? Trends Endocrinol Metab. 2003 Oct; 14(8):365-70. PMID: 14516934.
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    35. Sam S, Molitch ME. Timing and special concerns regarding endocrine surgery during pregnancy. Endocrinol Metab Clin North Am. 2003 Jun; 32(2):337-54. PMID: 12800535.
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    36. Kamradt MC, Chen F, Sam S, Cryns VL. The small heat shock protein alpha B-crystallin negatively regulates apoptosis during myogenic differentiation by inhibiting caspase-3 activation. J Biol Chem. 2002 Oct 11; 277(41):38731-6. PMID: 12140279.
      View in: PubMed
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