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Karla Temple

Title
InstitutionUniversity of Chicago
AddressChicago IL 60637
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    Collapse Biography 
    Collapse education and training
    Miami University, Oxford, OHBS08/1990Dietetics
    The Ohio State University, Columbus, OHMS08/1997Human Nutrition
    The Ohio State University, Columbus, OH08/1997AP IV Dietetic Internship
    University of Chicago, Chicago, ILPhD08/2004Molecular Metabolism and Nutrition
    Collapse awards and honors
    1997Outstanding Dietic Intern for the State of Ohio, The Ohio State University

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Shams-White MM, Tjaden AH, Edelstein SL, Bassiouni S, Kahle LL, Kim C, Pi-Sunyer X, Temple KA, Venditti EM, Reedy J, Heckman-Stoddard BM, DPP Research Group. The 2018 World Cancer Research Fund (WCRF)/American Institute for Cancer Research (AICR) score and diabetes risk in the Diabetes Prevention Program Outcomes Study (DPPOS). BMC Nutr. 2022 Sep 21; 8(1):105. PMID: 36131333; PMCID: PMC9494851.
      Citations:    
    2. Mokhlesi B, Tjaden AH, Temple KA, Edelstein SL, Sam S, Nadeau KJ, Hannon TS, Manchanda S, Mather KJ, Kahn SE, Ehrmann DA, Van Cauter E, RISE Consortium. Obstructive Sleep Apnea, Glucose Tolerance, and ß-Cell Function in Adults With Prediabetes or Untreated Type 2 Diabetes in the Restoring Insulin Secretion (RISE) Study. Diabetes Care. 2021 04; 44(4):993-1001. PMID: 33547205; PMCID: PMC7985427.
      Citations: 13     Fields:    Translation:Humans
    3. Allaire BT, Tjaden AH, Venditti EM, Apolzan JW, Dabelea D, Delahanty LM, Edelstein SL, Hoskin MA, Temple KA, Wylie-Rosett J, Jaacks LM, DPP Research Group. Diet quality, weight loss, and diabetes incidence in the Diabetes Prevention Program (DPP). BMC Nutr. 2020 Dec 15; 6(1):74. PMID: 33317629; PMCID: PMC7737274.
      Citations: 12     
    4. Mokhlesi B, Temple KA, Tjaden AH, Edelstein SL, Nadeau KJ, Hannon TS, Manchanda S, Sam S, Barengolts E, Utzschneider KM, Ehrmann DA, Van Cauter E, RISE Consortium. The association of sleep disturbances with glycemia and obesity in youth at risk for or with recently diagnosed type 2 diabetes. Pediatr Diabetes. 2019 12; 20(8):1056-1063. PMID: 31486162; PMCID: PMC7199716.
      Citations: 8     Fields:    Translation:Humans
    5. RISE Consortium. Obesity and insulin sensitivity effects on cardiovascular risk factors: Comparisons of obese dysglycemic youth and adults. Pediatr Diabetes. 2019 11; 20(7):849-860. PMID: 31301210; PMCID: PMC6786916.
      Citations: 2     Fields:    Translation:Humans
    6. RISE Consortium, RISE Consortium Investigators. Effects of Treatment of Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes With Metformin Alone or in Combination With Insulin Glargine on ß-Cell Function: Comparison of Responses In Youth And Adults. Diabetes. 2019 08; 68(8):1670-1680. PMID: 31178433; PMCID: PMC6692818.
      Citations: 58     Fields:    Translation:Humans
    7. RISE Consortium. Lack of Durable Improvements in ß-Cell Function Following Withdrawal of Pharmacological Interventions in Adults With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes. Diabetes Care. 2019 09; 42(9):1742-1751. PMID: 31178434; PMCID: PMC6702605.
      Citations: 36     Fields:    Translation:HumansCells
    8. Temple KA, Tjaden AH, Atkinson KM, Barengolts E, Hannon TS, Mather KJ, Utzschneider KM, Edelstein SL, Ehrmann DA, Mokhlesi B, RISE Consortium. Association of Habitual Daily Physical Activity With Glucose Tolerance and ß-Cell Function in Adults With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes From the Restoring Insulin Secretion (RISE) Study. Diabetes Care. 2019 08; 42(8):1521-1529. PMID: 31177181; PMCID: PMC6647043.
      Citations: 8     Fields:    Translation:HumansCells
    9. Mokhlesi B, Temple KA, Tjaden AH, Edelstein SL, Utzschneider KM, Nadeau KJ, Hannon TS, Sam S, Barengolts E, Manchanda S, Ehrmann DA, Van Cauter E, RISE Consortium. Association of Self-Reported Sleep and Circadian Measures With Glycemia in Adults With Prediabetes or Recently Diagnosed Untreated Type 2 Diabetes. Diabetes Care. 2019 07; 42(7):1326-1332. PMID: 31048411; PMCID: PMC6609965.
      Citations: 30     Fields:    Translation:Humans
    10. Morselli LL, Temple KA, Leproult R, Ehrmann DA, Van Cauter E, Mokhlesi B. Determinants of Slow-Wave Activity in Overweight and Obese Adults: Roles of Sex, Obstructive Sleep Apnea and Testosterone Levels. Front Endocrinol (Lausanne). 2018; 9:377. PMID: 30050500; PMCID: PMC6052085.
      Citations: 6     Fields:    
    11. Temple KA, Leproult R, Morselli L, Ehrmann DA, Van Cauter E, Mokhlesi B. Sex Differences in the Impact of Obstructive Sleep Apnea on Glucose Metabolism. Front Endocrinol (Lausanne). 2018; 9:376. PMID: 30042734; PMCID: PMC6048262.
      Citations: 10     Fields:    
    12. RISE Consortium. Metabolic Contrasts Between Youth and Adults With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes: II. Observations Using the Oral Glucose Tolerance Test. Diabetes Care. 2018 08; 41(8):1707-1716. PMID: 29941498; PMCID: PMC6054494.
      Citations: 62     Fields:    Translation:HumansCells
    13. RISE Consortium. Impact of Insulin and Metformin Versus Metformin Alone on ß-Cell Function in Youth With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes. Diabetes Care. 2018 08; 41(8):1717-1725. PMID: 29941500; PMCID: PMC6054504.
      Citations: 90     Fields:    Translation:HumansCells
    14. RISE Consortium. Metabolic Contrasts Between Youth and Adults With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes: I. Observations Using the Hyperglycemic Clamp. Diabetes Care. 2018 08; 41(8):1696-1706. PMID: 29941497; PMCID: PMC6054493.
      Citations: 92     Fields:    Translation:HumansCells
    15. RISE Consortium. Restoring Insulin Secretion (RISE): design of studies of ß-cell preservation in prediabetes and early type 2 diabetes across the life span. Diabetes Care. 2014; 37(3):780-8. PMID: 24194506; PMCID: PMC3931376.
      Citations: 63     Fields:    Translation:HumansCells
    16. Milewski WM, Temple KA, Wesselschmidt RL, Hara M. Generation of embryonic stem cells from mouse insulin I promoter-green fluorescent protein transgenic mice and characterization in a teratoma model. In Vitro Cell Dev Biol Anim. 2009 Jan-Feb; 45(1-2):1-5. PMID: 18855079; PMCID: PMC2694942.
      Citations: 3     Fields:    
    17. Sinkevicius KW, Burdette JE, Woloszyn K, Hewitt SC, Hamilton K, Sugg SL, Temple KA, Wondisford FE, Korach KS, Woodruff TK, Greene GL. An estrogen receptor-alpha knock-in mutation provides evidence of ligand-independent signaling and allows modulation of ligand-induced pathways in vivo. Endocrinology. 2008 Jun; 149(6):2970-9. PMID: 18339713; PMCID: PMC2408815.
      Citations: 30     Fields:    
    18. Kim J, Temple KA, Jones SA, Meredith KN, Basko JL, Brady MJ. Differential modulation of 3T3-L1 adipogenesis mediated by 11beta-hydroxysteroid dehydrogenase-1 levels. J Biol Chem. 2007 Apr 13; 282(15):11038-46. PMID: 17311922.
      Citations: 11     Fields:    Translation:AnimalsCells
    19. Temple KA, Basko X, Allison MB, Brady MJ. Uncoupling of 3T3-L1 gene expression from lipid accumulation during adipogenesis. FEBS Lett. 2007 Feb 06; 581(3):469-74. PMID: 17239864; PMCID: PMC1803685.
      Citations: 4     Fields:    Translation:AnimalsCells
    20. Iyengar P, Espina V, Williams TW, Lin Y, Berry D, Jelicks LA, Lee H, Temple K, Graves R, Pollard J, Chopra N, Russell RG, Sasisekharan R, Trock BJ, Lippman M, Calvert VS, Petricoin EF, Liotta L, Dadachova E, Pestell RG, Lisanti MP, Bonaldo P, Scherer PE. Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment. J Clin Invest. 2005 May; 115(5):1163-76. PMID: 15841211; PMCID: PMC1077173.
      Citations: 180     Fields:    
    21. Yu C, Markan K, Temple KA, Deplewski D, Brady MJ, Cohen RN. The nuclear receptor corepressors NCoR and SMRT decrease peroxisome proliferator-activated receptor gamma transcriptional activity and repress 3T3-L1 adipogenesis. J Biol Chem. 2005 Apr 08; 280(14):13600-5. PMID: 15691842.
      Citations: 106     Fields:    Translation:AnimalsCells
    22. Temple KA, Cohen RN, Wondisford SR, Yu C, Deplewski D, Wondisford FE. An intact DNA-binding domain is not required for peroxisome proliferator-activated receptor gamma (PPARgamma) binding and activation on some PPAR response elements. J Biol Chem. 2005 Feb 04; 280(5):3529-40. PMID: 15572375.
      Citations: 13     Fields:    Translation:AnimalsCells
    23. Zhou XY, Shibusawa N, Naik K, Porras D, Temple K, Ou H, Kaihara K, Roe MW, Brady MJ, Wondisford FE. Insulin regulation of hepatic gluconeogenesis through phosphorylation of CREB-binding protein. Nat Med. 2004 Jun; 10(6):633-7. PMID: 15146178.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    24. Temple KA, Smith AM, Cockram DB. Selenate-supplemented nutritional formula increases plasma selenium in hemodialysis patients. J Ren Nutr. 2000 Jan; 10(1):16-23. PMID: 10671629.
      Citations: 4     Fields:    Translation:HumansCellsCTClinical Trials
    25. . Selenium Metabolism and Renal Disease. Journal of Renal Nutrition. 1997; 7(2):69-72. View Publication.
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