 Trypsinogen
"Trypsinogen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The inactive proenzyme of trypsin secreted by the pancreas, activated in the duodenum via cleavage by enteropeptidase. (Stedman, 25th ed)
| Descriptor ID |
D014362
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| MeSH Number(s) |
D08.622.885
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Trypsinogen".
Below are MeSH descriptors whose meaning is more specific than "Trypsinogen".
This graph shows the total number of publications written about "Trypsinogen" by people in this website by year, and whether "Trypsinogen" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Trypsinogen" by people in Profiles.
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Normatov I, Sentongo T. Pancreatic Malnutrition in Children. Pediatr Ann. 2019 Nov 01; 48(11):e441-e447.
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Whitcomb DC, LaRusch J, Krasinskas AM, Klei L, Smith JP, Brand RE, Neoptolemos JP, Lerch MM, Tector M, Sandhu BS, Guda NM, Orlichenko L. Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. Nat Genet. 2012 Dec; 44(12):1349-54.
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Nicodemus-Johnson J, Silic S, Ghigliotti L, Pisano E, Cheng CH. Assembly of the antifreeze glycoprotein/trypsinogen-like protease genomic locus in the Antarctic toothfish Dissostichus mawsoni (Norman). Genomics. 2011 Sep; 98(3):194-201.
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Bhatia E, Choudhuri G, Sikora SS, Landt O, Kage A, Becker M, Witt H. Tropical calcific pancreatitis: strong association with SPINK1 trypsin inhibitor mutations. Gastroenterology. 2002 Oct; 123(4):1020-5.
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Kossiakoff AA, Chambers JL, Kay LM, Stroud RM. Structure of bovine trypsinogen at 1.9 A resolution. Biochemistry. 1977 Feb 22; 16(4):654-64.
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Stroud RM, Kossiakoff AA, Chambers JL. Mechanisms of zymogen activation. Annu Rev Biophys Bioeng. 1977; 6:177-93.
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