 Antibodies, Antineutrophil Cytoplasmic
"Antibodies, Antineutrophil Cytoplasmic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Autoantibodies directed against cytoplasmic constituents of POLYMORPHONUCLEAR LEUKOCYTES and/or MONOCYTES. They are used as specific markers for WEGENER GRANULOMATOSIS and other diseases, though their pathophysiological role is not clear. ANCA are routinely detected by indirect immunofluorescence with three different patterns: c-ANCA (cytoplasmic), p-ANCA (perinuclear), and atypical ANCA.
| Descriptor ID |
D019268
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| MeSH Number(s) |
D12.776.124.486.485.114.323.190 D12.776.124.790.651.114.323.190 D12.776.377.715.548.114.323.190 D23.101.050
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| Concept/Terms |
Antibodies, Antineutrophil Cytoplasmic- Antibodies, Antineutrophil Cytoplasmic
- Antineutrophil Cytoplasmic Antibody
- Antibody, Antineutrophil Cytoplasmic
- Cytoplasmic Antibody, Antineutrophil
- Anti-Neutrophil Cytoplasmic Antibody
- Anti Neutrophil Cytoplasmic Antibody
- Antibody, Anti-Neutrophil Cytoplasmic
- Cytoplasmic Antibody, Anti-Neutrophil
- Anti-Neutrophil Cytoplasmic Antibodies
- Anti Neutrophil Cytoplasmic Antibodies
- Antibodies, Anti-Neutrophil Cytoplasmic
- Cytoplasmic Antibodies, Anti-Neutrophil
- ANCA
- Antineutrophil Cytoplasmic Antibodies
- Cytoplasmic Antibodies, Antineutrophil
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Below are MeSH descriptors whose meaning is more general than "Antibodies, Antineutrophil Cytoplasmic".
Below are MeSH descriptors whose meaning is more specific than "Antibodies, Antineutrophil Cytoplasmic".
This graph shows the total number of publications written about "Antibodies, Antineutrophil Cytoplasmic" by people in this website by year, and whether "Antibodies, Antineutrophil Cytoplasmic" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2010 | 3 | 0 | 3 | | 2014 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Antibodies, Antineutrophil Cytoplasmic" by people in Profiles.
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Morishita KA, Wagner-Weiner L, Yen EY, Sivaraman V, James KE, Gerstbacher D, Szymanski AM, O'Neil KM, Cabral DA. Consensus Treatment Plans for Severe Pediatric Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Care Res (Hoboken). 2022 09; 74(9):1550-1558.
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Liu GY, Ventura IB, Achtar-Zadeh N, Elicker BM, Jones KD, Wolters PJ, Collard HR, Adegunsoye A, Strek ME, Ley B. Prevalence and Clinical Significance of Antineutrophil Cytoplasmic Antibodies in North American Patients With Idiopathic Pulmonary Fibrosis. Chest. 2019 10; 156(4):715-723.
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Bertha M, Vasantharoopan A, Kumar A, Bruce BB, Prince J, Hofmekler T, Okou D, Chopra P, Wang G, Sauer C, Landers CJ, Hussain SZ, Cross RK, Baldassano RN, Kappelman MD, Katz J, Alexander JS, Kirschner BS, Moulton DE, Osuntokun BO, Patel A, Saeed S, Klapproth JA, Dhere TA, Dubinsky MC, McGovern D, Kugathasan S. IBD Serology and Disease Outcomes in African Americans With Crohn's Disease. Inflamm Bowel Dis. 2017 12 19; 24(1):209-216.
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Cabral DA, Canter DL, Muscal E, Nanda K, Wahezi DM, Spalding SJ, Twilt M, Benseler SM, Campillo S, Charuvanij S, Dancey P, Eberhard BA, Elder ME, Hersh A, Higgins GC, Huber AM, Khubchandani R, Kim S, Klein-Gitelman M, Kostik MM, Lawson EF, Lee T, Lubieniecka JM, McCurdy D, Moorthy LN, Morishita KA, Nielsen SM, O'Neil KM, Reiff A, Ristic G, Robinson AB, Sarmiento A, Shenoi S, Toth MB, Van Mater HA, Wagner-Weiner L, Weiss JE, White AJ, Yeung RS. Comparing Presenting Clinical Features in 48 Children With Microscopic Polyangiitis to 183 Children Who Have Granulomatosis With Polyangiitis (Wegener's): An ARChiVe Cohort Study. Arthritis Rheumatol. 2016 10; 68(10):2514-26.
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Khalighi MA, Wang S, Henriksen KJ, Bock M, Keswani M, Chang A, Meehan SM. Pauci-immune glomerulonephritis in children: a clinicopathologic study of 21 patients. Pediatr Nephrol. 2015 Jun; 30(6):953-9.
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Zhao L, David MZ, Hyjek E, Chang A, Meehan SM. M2 macrophage infiltrates in the early stages of ANCA-associated pauci-immune necrotizing GN. Clin J Am Soc Nephrol. 2015 Jan 07; 10(1):54-62.
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Henriksen KJ, Hong RB, Sobrero MI, Chang A. Rare association of chronic lymphocytic leukemia/small lymphocytic lymphoma, ANCAs, and pauci-immune crescentic glomerulonephritis. Am J Kidney Dis. 2011 Jan; 57(1):170-4.
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Gmurczyk A, Ahya SN, Goldschmidt R, Kim G, Ho LT, Nash K. A case of simultaneous, biopsy-proven, classic, ANCA-positive Wegener's granulomatosis and anti-GBM disease, but without detectable circulating anti-GBM antibodies. ScientificWorldJournal. 2010 Jun 15; 10:1078-83.
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Marinopoulos SS, Coylewright M, Auwaerter PG, Flynn JA. Clinical problem-solving. More than meets the ear. N Engl J Med. 2010 Apr 01; 362(13):1228-33.
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Desai A, Goldschmidt RA, Kim GC. Sequential development of pulmonary renal syndrome associated with c-ANCA 3 years after development of anti-GBM glomerulonephritis. Nephrol Dial Transplant. 2007 Mar; 22(3):926-9.
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