Immunoglobulins, Thyroid-Stimulating
"Immunoglobulins, Thyroid-Stimulating" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Autoantibodies that bind to the thyroid-stimulating hormone (TSH) receptor (RECEPTORS, THYROTROPIN) on thyroid epithelial cells. The autoantibodies mimic TSH causing an unregulated production of thyroid hormones characteristic of GRAVES DISEASE.
| Descriptor ID |
D018828
|
| MeSH Number(s) |
D12.776.124.486.485.114.323.480 D12.776.124.790.651.114.323.480 D12.776.377.715.548.114.323.480
|
| Concept/Terms |
Immunoglobulins, Thyroid-Stimulating- Immunoglobulins, Thyroid-Stimulating
- Antibodies, Thyroid-Stimulating
- Thyroid-Stimulating Antibodies
- Thyroid Stimulating Antibodies
- Thyroid-Stimulating Immunoglobulin
- Thyroid Stimulating Immunoglobulin
- Thyroid-Stimulating Immunoglobulins
- Thyroid Stimulating Immunoglobulins
- Thyroid Stimulating Antibody
- Antibody, Thyroid Stimulating
- Stimulating Antibody, Thyroid
- Immunoglobulin, Thyroid-Stimulating
- Immunoglobulin, Thyroid Stimulating
|
Below are MeSH descriptors whose meaning is more general than "Immunoglobulins, Thyroid-Stimulating".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulins, Thyroid-Stimulating".
This graph shows the total number of publications written about "Immunoglobulins, Thyroid-Stimulating" by people in this website by year, and whether "Immunoglobulins, Thyroid-Stimulating" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 2000 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "Immunoglobulins, Thyroid-Stimulating" by people in Profiles.
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Negative correlation between bone mineral density and TSH receptor antibodies in male patients with untreated Graves' disease. Osteoporos Int. 2006; 17(7):1103-10.
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Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity. Mol Endocrinol. 2004 Dec; 18(12):3020-34.
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Genetic immunization of outbred mice with thyrotropin receptor cDNA provides a model of Graves' disease. J Clin Invest. 2000 Mar; 105(6):803-11.
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Production of thyroid-stimulating antibodies in mice by immunization with T-cell epitopes of human thyrotropin receptor. Endocrinology. 1995 Apr; 136(4):1642-7.
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T-cells recognize multiple epitopes in the human thyrotropin receptor extracellular domain. J Clin Endocrinol Metab. 1995 Mar; 80(3):905-14.