 Extracellular Matrix Proteins
"Extracellular Matrix Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Macromolecular organic compounds that contain carbon, hydrogen, oxygen, nitrogen, and usually, sulfur. These macromolecules (proteins) form an intricate meshwork in which cells are embedded to construct tissues. Variations in the relative types of macromolecules and their organization determine the type of extracellular matrix, each adapted to the functional requirements of the tissue. The two main classes of macromolecules that form the extracellular matrix are: glycosaminoglycans, usually linked to proteins (proteoglycans), and fibrous proteins (e.g., COLLAGEN; ELASTIN; FIBRONECTINS; and LAMININ).
| Descriptor ID |
D016326
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| MeSH Number(s) |
D12.776.860.300
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Extracellular Matrix Proteins".
Below are MeSH descriptors whose meaning is more specific than "Extracellular Matrix Proteins".
This graph shows the total number of publications written about "Extracellular Matrix Proteins" by people in this website by year, and whether "Extracellular Matrix Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1988 | 2 | 0 | 2 | | 1990 | 3 | 0 | 3 | | 1991 | 1 | 0 | 1 | | 1992 | 1 | 1 | 2 | | 1993 | 3 | 1 | 4 | | 1994 | 2 | 0 | 2 | | 1995 | 3 | 0 | 3 | | 1996 | 4 | 1 | 5 | | 1997 | 3 | 0 | 3 | | 1998 | 1 | 1 | 2 | | 1999 | 3 | 2 | 5 | | 2000 | 2 | 0 | 2 | | 2001 | 2 | 2 | 4 | | 2002 | 1 | 0 | 1 | | 2003 | 3 | 3 | 6 | | 2004 | 4 | 2 | 6 | | 2005 | 3 | 3 | 6 | | 2006 | 2 | 1 | 3 | | 2007 | 3 | 4 | 7 | | 2008 | 0 | 2 | 2 | | 2009 | 3 | 2 | 5 | | 2010 | 2 | 3 | 5 | | 2011 | 2 | 0 | 2 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 1 | 2 | | 2014 | 1 | 2 | 3 | | 2015 | 1 | 2 | 3 | | 2016 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "Extracellular Matrix Proteins" by people in Profiles.
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Shih YC, Chen CL, Zhang Y, Mellor RL, Kanter EM, Fang Y, Wang HC, Hung CT, Nong JY, Chen HJ, Lee TH, Tseng YS, Chen CN, Wu CC, Lin SL, Yamada KA, Nerbonne JM, Yang KC. Endoplasmic Reticulum Protein TXNDC5 Augments Myocardial Fibrosis by Facilitating Extracellular Matrix Protein Folding and Redox-Sensitive Cardiac Fibroblast Activation. Circ Res. 2018 04 13; 122(8):1052-1068.
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Lyon SM, Mayampurath A, Song D, Ye J, Januszyk M, Rogers MR, Ralston A, Frim DM, He TC, Reid RR. Whole-Proteome Analysis of Human Craniosynostotic Tissue Suggests a Link between Inflammatory Signaling and Osteoclast Activation in Human Cranial Suture Patency. Plast Reconstr Surg. 2018 02; 141(2):250e-260e.
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Ishihara J, Fukunaga K, Ishihara A, Larsson HM, Potin L, Hosseinchi P, Galliverti G, Swartz MA, Hubbell JA. Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events. Sci Transl Med. 2017 Nov 08; 9(415).
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Zhavoronkov A, Izumchenko E, Kanherkar RR, Teka M, Cantor C, Manaye K, Sidransky D, West MD, Makarev E, Csoka AB. Pro-fibrotic pathway activation in trabecular meshwork and lamina cribrosa is the main driving force of glaucoma. Cell Cycle. 2016 06 17; 15(12):1643-52.
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Mezyk-Kopec R, Wyroba B, Stalinska K, Próchnicki T, Wiatrowska K, Kilarski WW, Swartz MA, Bereta J. ADAM17 Promotes Motility, Invasion, and Sprouting of Lymphatic Endothelial Cells. PLoS One. 2015; 10(7):e0132661.
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Majumder B, Baraneedharan U, Thiyagarajan S, Radhakrishnan P, Narasimhan H, Dhandapani M, Brijwani N, Pinto DD, Prasath A, Shanthappa BU, Thayakumar A, Surendran R, Babu GK, Shenoy AM, Kuriakose MA, Bergthold G, Horowitz P, Loda M, Beroukhim R, Agarwal S, Sengupta S, Sundaram M, Majumder PK. Predicting clinical response to anticancer drugs using an ex vivo platform that captures tumour heterogeneity. Nat Commun. 2015 Feb 27; 6:6169.
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Lu A, Zuo C, He Y, Chen G, Piao L, Zhang J, Xiao B, Shen Y, Tang J, Kong D, Alberti S, Chen D, Zuo S, Zhang Q, Yan S, Fei X, Yuan F, Zhou B, Duan S, Yu Y, Lazarus M, Su Y, Breyer RM, Funk CD, Yu Y. EP3 receptor deficiency attenuates pulmonary hypertension through suppression of Rho/TGF-ß1 signaling. J Clin Invest. 2015 Mar 02; 125(3):1228-42.
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Ferreira DS, Lin YA, Cui H, Hubbell JA, Reis RL, Azevedo HS. Molecularly engineered self-assembling membranes for cell-mediated degradation. Adv Healthc Mater. 2015 Mar 11; 4(4):602-12.
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Martino MM, Briquez PS, Güç E, Tortelli F, Kilarski WW, Metzger S, Rice JJ, Kuhn GA, Müller R, Swartz MA, Hubbell JA. Growth factors engineered for super-affinity to the extracellular matrix enhance tissue healing. Science. 2014 Feb 21; 343(6173):885-8.
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Weaver KN, El Hallek M, Hopkin RJ, Sund KL, Henrickson M, Del Gaudio D, Yuksel A, Acar GO, Bober MB, Kim J, Boyadjiev SA. Keutel syndrome: report of two novel MGP mutations and discussion of clinical overlap with arylsulfatase E deficiency and relapsing polychondritis. Am J Med Genet A. 2014 Apr; 164A(4):1062-8.
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