Latent TGF-beta Binding Proteins
"Latent TGF-beta Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of secreted multidomain proteins that were originally identified by their association with the latent form of TRANSFORMING GROWTH FACTORS. They interact with a variety of EXTRACELLULAR MATRIX PROTEINS and may play a role in the regulation of TGB-beta bioavailability.
| Descriptor ID |
D053779
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| MeSH Number(s) |
D12.776.860.300.688
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Latent TGF-beta Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "Latent TGF-beta Binding Proteins".
This graph shows the total number of publications written about "Latent TGF-beta Binding Proteins" by people in this website by year, and whether "Latent TGF-beta Binding Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Latent TGF-beta Binding Proteins" by people in Profiles.
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Anti-latent TGFß binding protein 4 antibody improves muscle function and reduces muscle fibrosis in muscular dystrophy. Sci Transl Med. 2021 Sep 08; 13(610):eabf0376.
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Transcriptomic Signature of Right Ventricular Failure in Experimental Pulmonary Arterial Hypertension: Deep Sequencing Demonstrates Mitochondrial, Fibrotic, Inflammatory and Angiogenic Abnormalities. Int J Mol Sci. 2018 Sep 12; 19(9).
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Genetic modifiers of muscular dystrophy act on sarcolemmal resealing and recovery from injury. PLoS Genet. 2017 Oct; 13(10):e1007070.
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Targeting latent TGFß release in muscular dystrophy. Sci Transl Med. 2014 Oct 22; 6(259):259ra144.
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Excess SMAD signaling contributes to heart and muscle dysfunction in muscular dystrophy. Hum Mol Genet. 2014 Dec 20; 23(25):6722-31.
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LTBP4 genotype predicts age of ambulatory loss in Duchenne muscular dystrophy. Ann Neurol. 2013 Apr; 73(4):481-8.
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Mechanisms of muscle weakness in muscular dystrophy. J Gen Physiol. 2010 Jul; 136(1):29-34.
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Latent TGF-beta-binding protein 4 modifies muscular dystrophy in mice. J Clin Invest. 2009 Dec; 119(12):3703-12.