 Methimazole
"Methimazole" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.
| Descriptor ID |
D008713
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| MeSH Number(s) |
D02.886.489.600 D03.383.129.308.535
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| Concept/Terms |
Methimazole- Methimazole
- Mercasolyl
- Mercazolyl
- Merkazolil
- Tiamazol
- Methymazol
- Thiamazole
- Thimazol
- 1-Methyl-2-mercaptoimidazole
- 1 Methyl 2 mercaptoimidazole
- Methylmercaptoimidazole
Tapazole- Tapazole
- Jones Brand of Methimazole
- Eli Lilly Brand of Methimazole
Tirodril- Tirodril
- Estedi Brand of Methimazole
Strumazol- Strumazol
- Nourypharma Brand of Methimazole
Thiamazol Henning- Thiamazol Henning
- Henning, Thiamazol
- Sanofi Synthelabo Brand of Methimazole
- Henning Berlin Brand of Methimazole
Thyrozol- Thyrozol
- Merck Brand of Methimazole
Favistan- Favistan
- Temmler Brand of Methimazole
Methizol- Methizol
- Philopharm Brand of Methimazole
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Below are MeSH descriptors whose meaning is more general than "Methimazole".
Below are MeSH descriptors whose meaning is more specific than "Methimazole".
This graph shows the total number of publications written about "Methimazole" by people in this website by year, and whether "Methimazole" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Methimazole" by people in Profiles.
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Knollman PD, Giese A, Bhayani MK. Surgical Intervention for Medically Refractory Hyperthyroidism. Pediatr Ann. 2016 May 01; 45(5):e171-5.
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Morte B, Ceballos A, Diez D, Grijota-Martínez C, Dumitrescu AM, Di Cosmo C, Galton VA, Refetoff S, Bernal J. Thyroid hormone-regulated mouse cerebral cortex genes are differentially dependent on the source of the hormone: a study in monocarboxylate transporter-8- and deiodinase-2-deficient mice. Endocrinology. 2010 May; 151(5):2381-7.
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Moeller LC, Wardrip C, Niekrasz M, Refetoff S, Weiss RE. Comparison of thyroidectomized calf serum and stripped serum for the study of thyroid hormone action in human skin fibroblasts in vitro. Thyroid. 2009 Jun; 19(6):639-44.
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Lisi S, Pinchera A, McCluskey RT, Willnow TE, Refetoff S, Marcocci C, Vitti P, Menconi F, Grasso L, Luchetti F, Collins AB, Marino M. Preferential megalin-mediated transcytosis of low-hormonogenic thyroglobulin: a control mechanism for thyroid hormone release. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):14858-63.
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Cristovão FC, Bisi H, Mendonça BB, Bianco AC, Bloise W. Severe and mild neonatal hypothyroidism mediate opposite effects on Leydig cells of rats. Thyroid. 2002 Jan; 12(1):13-8.
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Ribeiro MO, Lebrun FL, Christoffolete MA, Branco M, Crescenzi A, Carvalho SD, Negrão N, Bianco AC. Evidence of UCP1-independent regulation of norepinephrine-induced thermogenesis in brown fat. Am J Physiol Endocrinol Metab. 2000 Aug; 279(2):E314-22.
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Duck SC, Sty J. Technetium thyroid uptake ratios in pediatric Graves disease. J Pediatr. 1985 Dec; 107(6):905-9.
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Klementschitsch P, Shen KL, Kaplan EL. Reemergence of thyroidectomy as treatment for Graves' disease. Surg Clin North Am. 1979 Feb; 59(1):35-44.
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Refetoff S, Demeester-Mirkine N, Ermans AM, DeGroot LJ. Rapid control of thyrotoxicosis with combined 131I, anthithyroid drugs and KI therapy. J Nucl Med Allied Sci. 1977 Jan-Jun; 21(1-2):23-9.
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Refetoff S, Ochi Y, Selenkow HA, Rosenfield RL. Neonatal hypothyroidism and goiter in one infant of each of two sets of twins due to maternal therapy with antithyroid drugs. J Pediatr. 1974 Aug; 85(2):240-4.
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