"Mesna" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from ANTINEOPLASTIC AGENTS, such as IFOSFAMIDE or CYCLOPHOSPHAMIDE.
| Descriptor ID |
D015080
|
| MeSH Number(s) |
D02.455.326.146.100.050.490 D02.886.489.590 D02.886.645.600.055.050.500
|
| Concept/Terms |
Mesna- Mesna
- Sodium 2-Mercaptoethanesulphonate
- 2-Mercaptoethanesulphonate, Sodium
|
Below are MeSH descriptors whose meaning is more general than "Mesna".
Below are MeSH descriptors whose meaning is more specific than "Mesna".
This graph shows the total number of publications written about "Mesna" by people in this website by year, and whether "Mesna" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mesna" by people in Profiles.
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Targeting bone marrow lymphoid niches in acute lymphoblastic leukemia. Leuk Res. 2015 Dec; 39(12):1437-42.
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Metformin exhibits radiation countermeasures efficacy when used alone or in combination with sulfhydryl containing drugs. Radiat Res. 2014 May; 181(5):464-70.
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Phase II randomized study of dose-dense docetaxel and cisplatin every 2 weeks with pegfilgrastim and darbepoetin alfa with and without the chemoprotector BNP7787 in patients with advanced non-small cell lung cancer (CALGB 30303). J Thorac Oncol. 2008 Oct; 3(10):1159-65.
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Protein-cross-linked polymeric materials through site-selective bioconjugation. Angew Chem Int Ed Engl. 2008; 47(20):3751-4.
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Delayed radioprotection by NFkappaB-mediated induction of Sod2 (MnSOD) in SA-NH tumor cells after exposure to clinically used thiol-containing drugs. Radiat Res. 2004 Nov; 162(5):536-46.
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Toxicity and efficacy of intensive chemotherapy for children with acute lymphoblastic leukemia (ALL) after first bone marrow or extramedullary relapse. Pediatr Blood Cancer. 2004 Oct; 43(5):571-9.
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Radioprotectants: current status and new directions. Oncology. 2002; 63 Suppl 2:2-10.
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Radiation therapy for consolidation of metastatic or recurrent sarcomas in children treated with intensive chemotherapy and stem cell rescue. A feasibility study. Int J Radiat Oncol Biol Phys. 1999 Jun 01; 44(3):569-77.
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Ifosfamide-based combination chemotherapy in advanced non-small cell lung cancer: two phase I studies. Semin Oncol. 1996 Jun; 23(3 Suppl 6):11-5.