Activin Receptors, Type I
"Activin Receptors, Type I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the two types of ACTIVIN RECEPTORS or activin receptor-like kinases (ALK'S). There are several type I activin receptors. The major active ones are ALK-2 (ActR-IA) and ALK-4 (ActR-IB).
| Descriptor ID |
D030201
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| MeSH Number(s) |
D08.811.913.696.620.682.700.062.500 D12.776.543.750.750.400.820.500.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Activin Receptors, Type I".
Below are MeSH descriptors whose meaning is more specific than "Activin Receptors, Type I".
This graph shows the total number of publications written about "Activin Receptors, Type I" by people in this website by year, and whether "Activin Receptors, Type I" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 2 | 1 | 3 |
| 2010 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Activin Receptors, Type I" by people in Profiles.
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Insight into Molecular Mechanism for Activin A-Induced Bone Morphogenetic Protein Signaling. Int J Mol Sci. 2020 Sep 05; 21(18).
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BMP signaling mediated by constitutively active Activin type 1 receptor (ACVR1) results in ectopic bone formation localized to distal extremity joints. Dev Biol. 2015 Apr 15; 400(2):202-9.
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Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma. Nat Genet. 2014 May; 46(5):462-6.
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Genetic variation within the hypothalamus-pituitary-ovarian axis in women with recurrent miscarriage. Hum Reprod. 2010 Oct; 25(10):2664-71.
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TGFbeta/BMP type I receptors ALK1 and ALK2 are essential for BMP9-induced osteogenic signaling in mesenchymal stem cells. J Biol Chem. 2010 Sep 17; 285(38):29588-98.
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Somatic acquisition and signaling of TGFBR1*6A in cancer. JAMA. 2005 Oct 05; 294(13):1634-46.
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ALK5 and Smad4 are involved in TGF-beta1-induced pulmonary endothelial permeability. FEBS Lett. 2005 Jul 18; 579(18):4031-7.
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TGFBR1*6A may contribute to hereditary colorectal cancer. J Clin Oncol. 2005 May 01; 23(13):3074-8.
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Combined genetic assessment of transforming growth factor-beta signaling pathway variants may predict breast cancer risk. Cancer Res. 2005 Apr 15; 65(8):3454-61.
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No major association between TGFBR1*6A and prostate cancer. BMC Genet. 2004 Sep 22; 5:28.