Mutagenesis, Site-Directed
"Mutagenesis, Site-Directed" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genetically engineered MUTAGENESIS at a specific site in the DNA molecule that introduces a base substitution, or an insertion or deletion.
| Descriptor ID |
D016297
|
| MeSH Number(s) |
E05.393.420.601.575
|
| Concept/Terms |
Mutagenesis, Site-Directed- Mutagenesis, Site-Directed
- Mutagenesis, Site Directed
- Site-Specific Mutagenesis
- Site Specific Mutagenesis
- Mutagenesis, Site-Specific
- Mutageneses, Site-Specific
- Mutagenesis, Site Specific
- Site-Specific Mutageneses
- Site-Directed Mutagenesis
- Mutageneses, Site-Directed
- Site Directed Mutagenesis
- Site-Directed Mutageneses
Oligonucleotide-Directed Mutagenesis- Oligonucleotide-Directed Mutagenesis
- Oligonucleotide Directed Mutagenesis
- Mutagenesis, Oligonucleotide-Directed
- Mutageneses, Oligonucleotide-Directed
- Mutagenesis, Oligonucleotide Directed
- Oligonucleotide-Directed Mutageneses
|
Below are MeSH descriptors whose meaning is more general than "Mutagenesis, Site-Directed".
Below are MeSH descriptors whose meaning is more specific than "Mutagenesis, Site-Directed".
This graph shows the total number of publications written about "Mutagenesis, Site-Directed" by people in this website by year, and whether "Mutagenesis, Site-Directed" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 3 | 5 | 8 |
| 1994 | 0 | 11 | 11 |
| 1995 | 0 | 4 | 4 |
| 1996 | 0 | 8 | 8 |
| 1997 | 0 | 5 | 5 |
| 1998 | 0 | 10 | 10 |
| 1999 | 0 | 7 | 7 |
| 2000 | 0 | 10 | 10 |
| 2001 | 0 | 14 | 14 |
| 2002 | 0 | 20 | 20 |
| 2003 | 0 | 14 | 14 |
| 2004 | 1 | 15 | 16 |
| 2005 | 2 | 11 | 13 |
| 2006 | 0 | 13 | 13 |
| 2007 | 0 | 7 | 7 |
| 2008 | 0 | 9 | 9 |
| 2009 | 0 | 14 | 14 |
| 2010 | 0 | 10 | 10 |
| 2011 | 0 | 4 | 4 |
| 2012 | 0 | 4 | 4 |
| 2013 | 0 | 10 | 10 |
| 2014 | 0 | 4 | 4 |
| 2015 | 0 | 4 | 4 |
| 2016 | 0 | 4 | 4 |
| 2017 | 0 | 2 | 2 |
| 2018 | 0 | 2 | 2 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mutagenesis, Site-Directed" by people in Profiles.
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Engineering Phage Host-Range and Suppressing Bacterial Resistance through Phage Tail Fiber Mutagenesis. Cell. 2019 10 03; 179(2):459-469.e9.
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Engineering allosteric regulation in protein kinases. Sci Signal. 2018 11 06; 11(555).
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A CLC-type F-/H+ antiporter in ion-swapped conformations. Nat Struct Mol Biol. 2018 07; 25(7):601-606.
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SIRT2 regulates oxidative stress-induced cell death through deacetylation of c-Jun NH2-terminal kinase. Cell Death Differ. 2018 09; 25(9):1638-1656.
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Mutations of AKT3 are associated with a wide spectrum of developmental disorders including extreme megalencephaly. Brain. 2017 Oct 01; 140(10):2610-2622.
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Engineering and Functional Characterization of Fusion Genes Identifies Novel Oncogenic Drivers of Cancer. Cancer Res. 2017 07 01; 77(13):3502-3512.
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ADAM12 induction by Twist1 promotes tumor invasion and metastasis via regulation of invadopodia and focal adhesions. J Cell Sci. 2017 Jun 15; 130(12):2036-2048.
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Activation Mechanism of the Bacteroides fragilis Cysteine Peptidase, Fragipain. Biochemistry. 2016 07 26; 55(29):4077-84.
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A Protocol for Functional Assessment of Whole-Protein Saturation Mutagenesis Libraries Utilizing High-Throughput Sequencing. J Vis Exp. 2016 07 03; (113).
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The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels. Nat Commun. 2016 06 22; 7:11984.