 Microtubules
"Microtubules" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Slender, cylindrical filaments found in the cytoskeleton of plant and animal cells. They are composed of the protein TUBULIN and are influenced by TUBULIN MODULATORS.
| Descriptor ID |
D008870
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| MeSH Number(s) |
A11.284.430.214.190.750.602
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Microtubules".
Below are MeSH descriptors whose meaning is more specific than "Microtubules".
This graph shows the total number of publications written about "Microtubules" by people in this website by year, and whether "Microtubules" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 | | 1984 | 0 | 1 | 1 | | 1990 | 1 | 1 | 2 | | 1993 | 2 | 0 | 2 | | 1994 | 1 | 0 | 1 | | 1995 | 1 | 2 | 3 | | 1996 | 0 | 1 | 1 | | 1997 | 1 | 2 | 3 | | 1998 | 1 | 1 | 2 | | 1999 | 0 | 1 | 1 | | 2000 | 1 | 1 | 2 | | 2001 | 0 | 2 | 2 | | 2002 | 1 | 1 | 2 | | 2003 | 2 | 3 | 5 | | 2004 | 4 | 7 | 11 | | 2005 | 1 | 5 | 6 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 2 | 3 | | 2008 | 1 | 4 | 5 | | 2009 | 2 | 3 | 5 | | 2010 | 3 | 2 | 5 | | 2011 | 2 | 1 | 3 | | 2012 | 2 | 1 | 3 | | 2013 | 3 | 2 | 5 | | 2014 | 5 | 3 | 8 | | 2015 | 2 | 3 | 5 | | 2016 | 0 | 2 | 2 | | 2017 | 2 | 2 | 4 | | 2018 | 1 | 1 | 2 | | 2019 | 1 | 0 | 1 | | 2020 | 0 | 1 | 1 | | 2021 | 1 | 2 | 3 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Microtubules" by people in Profiles.
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Stormo AED, Shavarebi F, FitzGibbon M, Earley EM, Ahrendt H, Lum LS, Verschueren E, Swaney DL, Skibinski G, Ravisankar A, van Haren J, Davis EJ, Johnson JR, Von Dollen J, Balen C, Porath J, Crosio C, Mirescu C, Iaccarino C, Dauer WT, Nichols RJ, Wittmann T, Cox TC, Finkbeiner S, Krogan NJ, Oakes SA, Hiniker A. The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity. J Cell Biol. 2022 04 04; 221(4).
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Khomtchouk BB, Lee YS, Khan ML, Sun P, Mero D, Davidson MH. Targeting the cytoskeleton and extracellular matrix in cardiovascular disease drug discovery. Expert Opin Drug Discov. 2022 05; 17(5):443-460.
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Prisco SZ, Hartweck LM, Rose L, Lima PDA, Thenappan T, Archer SL, Prins KW. Inflammatory Glycoprotein 130 Signaling Links Changes in Microtubules and Junctophilin-2 to Altered Mitochondrial Metabolism and Right Ventricular Contractility. Circ Heart Fail. 2022 01; 15(1):e008574.
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Rich A, Glotzer M. Small GTPases modulate intrinsic and extrinsic forces that control epithelial folding in Drosophila embryos. Small GTPases. 2021 Sep-Nov; 12(5-6):416-428.
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Bertels Z, Singh H, Dripps I, Siegersma K, Tipton AF, Witkowski WD, Sheets Z, Shah P, Conway C, Mangutov E, Ao M, Petukhova V, Karumudi B, Petukhov PA, Baca SM, Rasenick MM, Pradhan AA. Neuronal complexity is attenuated in preclinical models of migraine and restored by HDAC6 inhibition. Elife. 2021 04 15; 10.
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Lu W, Lakonishok M, Liu R, Billington N, Rich A, Glotzer M, Sellers JR, Gelfand VI. Competition between kinesin-1 and myosin-V defines Drosophila posterior determination. Elife. 2020 02 14; 9.
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Adriaans IE, Basant A, Ponsioen B, Glotzer M, Lens SMA. PLK1 plays dual roles in centralspindlin regulation during cytokinesis. J Cell Biol. 2019 04 01; 218(4):1250-1264.
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Dobyns WB, Aldinger KA, Ishak GE, Mirzaa GM, Timms AE, Grout ME, Dremmen MHG, Schot R, Vandervore L, van Slegtenhorst MA, Wilke M, Kasteleijn E, Lee AS, Barry BJ, Chao KR, Szczaluba K, Kobori J, Hanson-Kahn A, Bernstein JA, Carr L, D'Arco F, Miyana K, Okazaki T, Saito Y, Sasaki M, Das S, Wheeler MM, Bamshad MJ, Nickerson DA. MACF1 Mutations Encoding Highly Conserved Zinc-Binding Residues of the GAR Domain Cause Defects in Neuronal Migration and Axon Guidance. Am J Hum Genet. 2018 12 06; 103(6):1009-1021.
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McIntosh JR, O'Toole E, Morgan G, Austin J, Ulyanov E, Ataullakhanov F, Gudimchuk N. Microtubules grow by the addition of bent guanosine triphosphate tubulin to the tips of curved protofilaments. J Cell Biol. 2018 08 06; 217(8):2691-2708.
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Stam S, Freedman SL, Banerjee S, Weirich KL, Dinner AR, Gardel ML. Filament rigidity and connectivity tune the deformation modes of active biopolymer networks. Proc Natl Acad Sci U S A. 2017 11 21; 114(47):E10037-E10045.
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