Pituitary Adenylate Cyclase-Activating Polypeptide
"Pituitary Adenylate Cyclase-Activating Polypeptide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multi-function neuropeptide that acts throughout the body by elevating intracellular cyclic AMP level via its interaction with PACAP RECEPTORS. Although first isolated from hypothalamic extracts and named for its action on the pituitary, it is widely distributed in the central and peripheral nervous systems. PACAP is important in the control of endocrine and homeostatic processes, such as secretion of pituitary and gut hormones and food intake.
| Descriptor ID |
D051219
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| MeSH Number(s) |
D12.644.276.860.887 D12.644.400.625 D12.776.467.860.887 D12.776.631.600.887 D12.776.631.650.625 D23.529.850.887
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pituitary Adenylate Cyclase-Activating Polypeptide".
Below are MeSH descriptors whose meaning is more specific than "Pituitary Adenylate Cyclase-Activating Polypeptide".
This graph shows the total number of publications written about "Pituitary Adenylate Cyclase-Activating Polypeptide" by people in this website by year, and whether "Pituitary Adenylate Cyclase-Activating Polypeptide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pituitary Adenylate Cyclase-Activating Polypeptide" by people in Profiles.
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Dipeptidyl Peptidase (DPP)-4 Inhibitors and Pituitary Adenylate Cyclase-Activating Polypeptide, a DPP-4 Substrate, Extend Neurite Outgrowth of Mouse Dorsal Root Ganglia Neurons: A Promising Approach in Diabetic Polyneuropathy Treatment. Int J Mol Sci. 2024 Aug 15; 25(16).
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Feeding and metabolism in mice lacking pituitary adenylate cyclase-activating polypeptide. Endocrinology. 2008 Apr; 149(4):1571-80.
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Systemic administration of pituitary adenylate cyclase-activating polypeptide maintains beta-cell mass and retards onset of hyperglycaemia in beta-cell-specific calmodulin-overexpressing transgenic mice. Eur J Endocrinol. 2005 May; 152(5):805-11.