Brain-Derived Neurotrophic Factor
"Brain-Derived Neurotrophic Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the nerve growth factor family of trophic factors. In the brain BDNF has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. (From Kendrew, The Encyclopedia of Molecular Biology, 1994)
| Descriptor ID |
D019208
|
| MeSH Number(s) |
D12.644.276.860.100 D12.776.467.860.100 D12.776.631.600.100 D23.529.850.100
|
| Concept/Terms |
Brain-Derived Neurotrophic Factor- Brain-Derived Neurotrophic Factor
- Brain Derived Neurotrophic Factor
- Factor, Brain-Derived Neurotrophic
- Neurotrophic Factor, Brain-Derived
- BDNF
|
Below are MeSH descriptors whose meaning is more general than "Brain-Derived Neurotrophic Factor".
Below are MeSH descriptors whose meaning is more specific than "Brain-Derived Neurotrophic Factor".
This graph shows the total number of publications written about "Brain-Derived Neurotrophic Factor" by people in this website by year, and whether "Brain-Derived Neurotrophic Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2005 | 2 | 0 | 2 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 1 | 2 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 2 | 3 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Brain-Derived Neurotrophic Factor" by people in Profiles.
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Missense variants in FRS3 affect body mass index in populations of diverse ancestries. Nat Commun. 2025 Mar 25; 16(1):2694.
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NMDAR-independent, cAMP-dependent antidepressant actions of ketamine. Mol Psychiatry. 2019 12; 24(12):1833-1843.
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Effects of Brain-Derived Neurotrophic Factor on MicroRNA Expression Profile in Human Endothelial Progenitor Cells. Cell Transplant. 2018 06; 27(6):1005-1009.
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Disruption of lipid-raft localized Gas/tubulin complexes by antidepressants: a unique feature of HDAC6 inhibitors, SSRI and tricyclic compounds. Neuropsychopharmacology. 2018 06; 43(7):1481-1491.
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Brain-derived neurotrophic factor differentially modulates excitability of two classes of hippocampal output neurons. J Neurophysiol. 2016 08 01; 116(2):466-71.
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Why may allopregnanolone help alleviate loneliness? Med Hypotheses. 2015 Dec; 85(6):947-52.
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Brain-derived neurotrophic factor (BDNF) and neurocognitive deficits in people with schizophrenia: a meta-analysis. Psychiatry Res. 2015 Mar 30; 226(1):1-13.
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Primate phencyclidine model of schizophrenia: sex-specific effects on cognition, brain derived neurotrophic factor, spine synapses, and dopamine turnover in prefrontal cortex. Int J Neuropsychopharmacol. 2014 Oct 31; 18(6).
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Fingolimod phosphate attenuates oligomeric amyloid ß-induced neurotoxicity via increased brain-derived neurotrophic factor expression in neurons. PLoS One. 2013; 8(4):e61988.
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CD4+ T cell-mediated neuroprotection is independent of T cell-derived BDNF in a mouse facial nerve axotomy model. Brain Behav Immun. 2012 Aug; 26(6):886-90.