Hepatocyte Nuclear Factor 1-alpha
"Hepatocyte Nuclear Factor 1-alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Hepatocyte nuclear factor 1-alpha is a transcription factor found in the LIVER; PANCREAS; and KIDNEY that regulates HOMEOSTASIS of GLUCOSE.
| Descriptor ID |
D051538
|
| MeSH Number(s) |
D12.776.260.262.500.500 D12.776.260.400.218.500 D12.776.660.352.500.500 D12.776.930.318.500.500
|
| Concept/Terms |
Hepatocyte Nuclear Factor 1-alpha- Hepatocyte Nuclear Factor 1-alpha
- Hepatocyte Nuclear Factor 1 alpha
- LFB1 Transcription Factor
- Liver-Specific Transcription Factor LF-B1
- Liver Specific Transcription Factor LF B1
- Albumin Proximal Factor
- HNF-1alpha
- HNF 1alpha
- Hepatocyte Nuclear Factor 1alpha
|
Below are MeSH descriptors whose meaning is more general than "Hepatocyte Nuclear Factor 1-alpha".
Below are MeSH descriptors whose meaning is more specific than "Hepatocyte Nuclear Factor 1-alpha".
This graph shows the total number of publications written about "Hepatocyte Nuclear Factor 1-alpha" by people in this website by year, and whether "Hepatocyte Nuclear Factor 1-alpha" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
| 1996 | 0 | 2 | 2 |
| 1997 | 0 | 6 | 6 |
| 1998 | 0 | 2 | 2 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 2 | 3 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 1 | 2 |
| 2013 | 0 | 2 | 2 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 3 | 0 | 3 |
| 2021 | 2 | 1 | 3 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hepatocyte Nuclear Factor 1-alpha" by people in Profiles.
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Objective and Subjective Sleep Patterns in Adults With Maturity-Onset Diabetes of the Young (MODY). Diabetes Care. 2023 03 01; 46(3):608-612.
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Tcf-1 promotes genomic instability and T cell transformation in response to aberrant ß-catenin activation. Proc Natl Acad Sci U S A. 2022 08 09; 119(32):e2201493119.
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TCF-1 controls Treg cell functions that regulate inflammation, CD8+ T cell cytotoxicity and severity of colon cancer. Nat Immunol. 2021 09; 22(9):1152-1162.
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The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude. J Exp Med. 2021 06 07; 218(6).
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Wnt-ß-catenin activation epigenetically reprograms Treg cells in inflammatory bowel disease and dysplastic progression. Nat Immunol. 2021 04; 22(4):471-484.
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Human islets expressing HNF1A variant have defective ß cell transcriptional regulatory networks. J Clin Invest. 2019 01 02; 129(1):246-251.
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TCF-1 and HEB cooperate to establish the epigenetic and transcription profiles of CD4+CD8+ thymocytes. Nat Immunol. 2018 12; 19(12):1366-1378.
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Pancreatic Histopathology of Human Monogenic Diabetes Due to Causal Variants in KCNJ11, HNF1A, GATA6, and LMNA. J Clin Endocrinol Metab. 2018 01 01; 103(1):35-45.
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Variation in Maturity-Onset Diabetes of the Young Genes Influence Response to Interventions for Diabetes Prevention. J Clin Endocrinol Metab. 2017 08 01; 102(8):2678-2689.
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Single-cell analysis defines the divergence between the innate lymphoid cell lineage and lymphoid tissue-inducer cell lineage. Nat Immunol. 2016 Mar; 17(3):269-76.