Hepatocyte Nuclear Factor 1-beta
"Hepatocyte Nuclear Factor 1-beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A hepatocyte nuclear factor that is closely related to HEPATOCYTE NUCLEAR FACTOR 1-ALPHA but is only weakly expressed in the LIVER. Mutations in hepatocyte nuclear factor 1-beta are associated with renal CYSTS and MATURITY-ONSET DIABETES MELLITUS type 5.
| Descriptor ID |
D051539
|
| MeSH Number(s) |
D12.776.260.262.500.750 D12.776.260.400.218.750 D12.776.660.352.500.750 D12.776.930.318.500.750
|
| Concept/Terms |
Hepatocyte Nuclear Factor 1-beta- Hepatocyte Nuclear Factor 1-beta
- Hepatocyte Nuclear Factor 1 beta
- Liver Specific Transcription Factor LF-B3
- Liver Specific Transcription Factor LF B3
- Variant Hepatic Nuclear Factor 1
- HNF-1beta
- HNF 1beta
- Hepatocyte Nuclear Factor-1beta
- Hepatocyte Nuclear Factor 1beta
|
Below are MeSH descriptors whose meaning is more general than "Hepatocyte Nuclear Factor 1-beta".
Below are MeSH descriptors whose meaning is more specific than "Hepatocyte Nuclear Factor 1-beta".
This graph shows the total number of publications written about "Hepatocyte Nuclear Factor 1-beta" by people in this website by year, and whether "Hepatocyte Nuclear Factor 1-beta" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 |
| 1997 | 0 | 6 | 6 |
| 1998 | 0 | 2 | 2 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hepatocyte Nuclear Factor 1-beta" by people in Profiles.
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Variation in Maturity-Onset Diabetes of the Young Genes Influence Response to Interventions for Diabetes Prevention. J Clin Endocrinol Metab. 2017 08 01; 102(8):2678-2689.
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Clear cell carcinoma of the pancreas: histopathologic features and a unique biomarker: hepatocyte nuclear factor-1beta. Mod Pathol. 2008 Sep; 21(9):1075-83.
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Sustained expression of hepatocyte nuclear factor-6 leads to loss of pancreatic beta-cells by apoptosis. Exp Clin Endocrinol Diabetes. 2007 Nov; 115(10):654-61.
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Control of pancreas and liver gene expression by HNF transcription factors. Science. 2004 Feb 27; 303(5662):1378-81.
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Genetic variants of hepatocyte nuclear factor-1beta in Chinese young-onset diabetic patients with nephropathy. J Diabetes Complications. 2003 Nov-Dec; 17(6):369-73.
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Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism. Diabetes. 2001 Nov; 50(11):2472-80.
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Regulation of the pancreatic pro-endocrine gene neurogenin3. Diabetes. 2001 May; 50(5):928-36.
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Nature or nurture: an insightful illustration from a Chinese family with hepatocyte nuclear factor-1 alpha diabetes (MODY3) Diabetologia. 2000 Jun; 43(6):816-8.
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A simple test for the high-frequency P291fsinsC mutation in the HNF1 alpha/MODY3 gene. Diabetologia. 2000 Jun; 43(6):818-9.
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Abnormal nephron development associated with a frameshift mutation in the transcription factor hepatocyte nuclear factor-1 beta. Kidney Int. 2000 Mar; 57(3):898-907.