"Janus Kinase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A Janus kinase subtype that is involved in signaling from a broad variety of CYTOKINE RECEPTORS.
| Descriptor ID |
D053613
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.124.100 D12.776.476.393.100
|
| Concept/Terms |
Janus Kinase 1- Janus Kinase 1
- JAK-1 Protein Tyrosine Kinase
- JAK 1 Protein Tyrosine Kinase
- JAK1 Protein Tyrosine Kinase
- Jak1 Kinase
|
Below are MeSH descriptors whose meaning is more general than "Janus Kinase 1".
Below are MeSH descriptors whose meaning is more specific than "Janus Kinase 1".
This graph shows the total number of publications written about "Janus Kinase 1" by people in this website by year, and whether "Janus Kinase 1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Janus Kinase 1" by people in Profiles.
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Combined use of tofacitinib (pan-JAK inhibitor) and ruxolitinib (a JAK1/2 inhibitor) for refractory T-cell prolymphocytic leukemia (T-PLL) with a JAK3 mutation. Leuk Lymphoma. 2019 07; 60(7):1626-1631.
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Sensory Neurons Co-opt Classical Immune Signaling Pathways to Mediate Chronic Itch. Cell. 2017 Sep 21; 171(1):217-228.e13.
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Hes3 regulates cell number in cultures from glioblastoma multiforme with stem cell characteristics. Sci Rep. 2013; 3:1095.
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Growth hormone synergizes with BMP9 in osteogenic differentiation by activating the JAK/STAT/IGF1 pathway in murine multilineage cells. J Bone Miner Res. 2012 Jul; 27(7):1566-75.
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Silencing of USP18 potentiates the antiviral activity of interferon against hepatitis C virus infection. Gastroenterology. 2006 Nov; 131(5):1584-91.
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Arsenic inhibition of the JAK-STAT pathway. Oncogene. 2004 Apr 29; 23(20):3603-12.
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Herpes simplex virus 1 gene products occlude the interferon signaling pathway at multiple sites. J Virol. 2004 Apr; 78(8):4185-96.
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The CrkL adapter protein is required for type I interferon-dependent gene transcription and activation of the small G-protein Rap1. Biochem Biophys Res Commun. 2002 Mar 08; 291(4):744-50.
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Zebrafish stat3 is expressed in restricted tissues during embryogenesis and stat1 rescues cytokine signaling in a STAT1-deficient human cell line. Dev Dyn. 1999 Aug; 215(4):352-70.
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Thymic stromal lymphopoietin: a cytokine that promotes the development of IgM+ B cells in vitro and signals via a novel mechanism. J Immunol. 1999 Jan 15; 162(2):677-83.