"Chaperonins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of multisubunit protein complexes that form into large cylindrical structures which bind to and encapsulate non-native proteins. Chaperonins utilize the energy of ATP hydrolysis to enhance the efficiency of PROTEIN FOLDING reactions and thereby help proteins reach their functional conformation. The family of chaperonins is split into GROUP I CHAPERONINS, and GROUP II CHAPERONINS, with each group having its own repertoire of protein subunits and subcellular preferences.
| Descriptor ID |
D018833
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| MeSH Number(s) |
D08.811.277.040.025.142 D12.776.580.216.210
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Chaperonins".
Below are MeSH descriptors whose meaning is more specific than "Chaperonins".
This graph shows the total number of publications written about "Chaperonins" by people in this website by year, and whether "Chaperonins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chaperonins" by people in Profiles.
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Protein folding: sticky N17 speeds huntingtin pile-up. Nat Chem Biol. 2010 Jan; 6(1):7-8.
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Protein evolution: innovative chaps. Curr Biol. 2009 Sep 15; 19(17):R740-2.
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Bacteroides fragilis synthesizes a DNA invertase affecting both a local and a distant region. J Bacteriol. 2007 Mar; 189(5):2119-24.
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WDRPUH, a novel WD-repeat-containing protein, is highly expressed in human hepatocellular carcinoma and involved in cell proliferation. Neoplasia. 2005 Apr; 7(4):348-55.
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Regulation of nicotinic acetylcholine receptor assembly. Ann N Y Acad Sci. 2003 Sep; 998:66-80.
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Mycobacterial DNA in recurrent sarcoidosis in the transplanted lung--a PCR-based study on four cases. Virchows Arch. 2000 Apr; 436(4):365-9.
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Cyclophilin catalyzes protein folding in yeast mitochondria. Proc Natl Acad Sci U S A. 1995 Jul 03; 92(14):6319-23.
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The protein import receptor of mitochondria. Trends Biochem Sci. 1995 Mar; 20(3):98-101.
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Fusion proteins containing the cytochrome b2 presequence are sorted to the mitochondrial intermembrane space independently of hsp60. J Biol Chem. 1994 Jun 24; 269(25):17279-88.
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Cyclic AMP-regulated AChR assembly is independent of AChR subunit phosphorylation by PKA. J Cell Sci. 1994 Jun; 107 ( Pt 6):1641-51.