"Molecular Chaperones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of cellular proteins that mediate the correct assembly or disassembly of polypeptides and their associated ligands. Although they take part in the assembly process, molecular chaperones are not components of the final structures.
| Descriptor ID |
D018832
|
| MeSH Number(s) |
D12.776.580
|
| Concept/Terms |
Molecular Chaperones- Molecular Chaperones
- Molecular Chaperone
- Chaperone, Molecular
- Chaperones, Molecular
|
Below are MeSH descriptors whose meaning is more general than "Molecular Chaperones".
Below are MeSH descriptors whose meaning is more specific than "Molecular Chaperones".
This graph shows the total number of publications written about "Molecular Chaperones" by people in this website by year, and whether "Molecular Chaperones" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 1999 | 3 | 0 | 3 |
| 2000 | 3 | 2 | 5 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 2 | 2 |
| 2003 | 1 | 5 | 6 |
| 2004 | 1 | 2 | 3 |
| 2005 | 1 | 3 | 4 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 3 | 3 |
| 2008 | 4 | 2 | 6 |
| 2009 | 1 | 1 | 2 |
| 2010 | 3 | 2 | 5 |
| 2011 | 1 | 2 | 3 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 4 | 3 | 7 |
| 2016 | 1 | 4 | 5 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 2 | 3 |
| 2022 | 2 | 2 | 4 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 3 | 4 |
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Below are the most recent publications written about "Molecular Chaperones" by people in Profiles.
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Preserve or destroy: Orphan protein proteostasis and the heat shock response. J Cell Biol. 2024 Dec 02; 223(12).
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MEN1/DAXX/ATRX mutations enhance progression-free survival in gastroenteropancreatic neuroendocrine tumors treated with peptide receptor radionuclide therapy. Endocr Relat Cancer. 2024 Nov 01; 31(11).
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The Heat Shock Response as a Condensate Cascade. J Mol Biol. 2024 Jul 15; 436(14):168642.
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Chaperone-assisted cryo-EM structure of P. aeruginosa PhuR reveals molecular basis for heme binding. Structure. 2024 Apr 04; 32(4):411-423.e6.
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Transcriptional regulation of Sis1 promotes fitness but not feedback in the heat shock response. Elife. 2023 05 09; 12.
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Mechanism of an intramembrane chaperone for multipass membrane proteins. Nature. 2022 11; 611(7934):161-166.
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Specific binding of Hsp27 and phosphorylated Tau mitigates abnormal Tau aggregation-induced pathology. Elife. 2022 Sep 01; 11.
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Listeria monocytogenes two component system PieRS regulates secretion chaperones PrsA1 and PrsA2 and enhances bacterial translocation across the intestine. Mol Microbiol. 2022 09; 118(3):278-293.
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Architecture of the cytoplasmic face of the nuclear pore. Science. 2022 06 10; 376(6598):eabm9129.
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The SARS-CoV-2 Programmed -1 Ribosomal Frameshifting Element Crystal Structure Solved to 2.09 Å Using Chaperone-Assisted RNA Crystallography. ACS Chem Biol. 2021 08 20; 16(8):1469-1481.