"CpG Islands" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Areas of increased density of the dinucleotide sequence cytosine--phosphate diester--guanine. They form stretches of DNA several hundred to several thousand base pairs long. In humans there are about 45,000 CpG islands, mostly found at the 5' ends of genes. They are unmethylated except for those on the inactive X chromosome and some associated with imprinted genes.
| Descriptor ID |
D018899
|
| MeSH Number(s) |
G02.111.570.080.380.160 G05.360.080.380.160 G05.360.340.024.159
|
| Concept/Terms |
CpG Islands- CpG Islands
- CpG Island
- Island, CpG
- Islands, CpG
- CpG-Rich Islands
- CpG Rich Islands
- CpG-Rich Island
- Island, CpG-Rich
- Islands, CpG-Rich
CpG Clusters- CpG Clusters
- Cluster, CpG
- Clusters, CpG
- CpG Cluster
|
Below are MeSH descriptors whose meaning is more general than "CpG Islands".
Below are MeSH descriptors whose meaning is more specific than "CpG Islands".
This graph shows the total number of publications written about "CpG Islands" by people in this website by year, and whether "CpG Islands" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 3 | 4 |
| 2003 | 1 | 3 | 4 |
| 2004 | 1 | 2 | 3 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 4 | 4 |
| 2008 | 0 | 2 | 2 |
| 2009 | 3 | 0 | 3 |
| 2010 | 0 | 4 | 4 |
| 2011 | 1 | 4 | 5 |
| 2012 | 1 | 6 | 7 |
| 2013 | 0 | 5 | 5 |
| 2014 | 1 | 5 | 6 |
| 2015 | 3 | 6 | 9 |
| 2016 | 1 | 4 | 5 |
| 2017 | 1 | 7 | 8 |
| 2018 | 0 | 9 | 9 |
| 2019 | 1 | 5 | 6 |
| 2020 | 0 | 3 | 3 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 3 | 3 |
| 2023 | 0 | 3 | 3 |
| 2024 | 2 | 0 | 2 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "CpG Islands" by people in Profiles.
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Differential DNA Methylation in the Benign and Cancerous Prostate Tissue of African American and European American Men. Cancer Epidemiol Biomarkers Prev. 2025 Mar 03; 34(3):428-438.
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DNA methylation correlates of chronological age in diverse human tissue types. Epigenetics Chromatin. 2024 Aug 08; 17(1):25.
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Association between gut microbiota and CpG island methylator phenotype in colorectal cancer. Gut Microbes. 2024 Jan-Dec; 16(1):2363012.
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DNA methylation entropy as a measure of stem cell replication and aging. Genome Biol. 2023 02 16; 24(1):27.
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TET1 and TDG Suppress Inflammatory Response in Intestinal Tumorigenesis: Implications for Colorectal Tumors With the CpG Island Methylator Phenotype. Gastroenterology. 2023 05; 164(6):921-936.e1.
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A functional genomics pipeline to identify high-value asthma and allergy CpGs in the human methylome. J Allergy Clin Immunol. 2023 06; 151(6):1609-1621.
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Non-pathogenic microbiota accelerate age-related CpG Island methylation in colonic mucosa. Epigenetics. 2023 12; 18(1):2160568.
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DNA methylation signatures in airway cells from adult children of asthmatic mothers reflect subtypes of severe asthma. Proc Natl Acad Sci U S A. 2022 06 14; 119(24):e2116467119.
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Acute lymphoblastic leukemia displays a distinct highly methylated genome. Nat Cancer. 2022 06; 3(6):768-782.
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Mutation saturation for fitness effects at human CpG sites. Elife. 2021 11 22; 10.