Chromosomes, Artificial, Human
"Chromosomes, Artificial, Human" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
DNA constructs that are composed of, at least, all elements, such as a REPLICATION ORIGIN; TELOMERE; and CENTROMERE, required for successful replication, propagation to and maintainance in progeny human cells. In addition, they are constructed to carry other sequences for analysis or gene transfer.
| Descriptor ID |
D022222
|
| MeSH Number(s) |
A11.284.187.178.190.117 A11.284.187.520.190.117 A11.284.187.520.300.117 G05.360.162.178.190.117 G05.360.162.520.190.117 G05.360.162.520.300.117 G05.360.337.249.190.117
|
| Concept/Terms |
Chromosomes, Artificial, Human- Chromosomes, Artificial, Human
- HACs (Chromosomes)
- Artificial Chromosomes, Human
- Artificial Chromosome, Human
- Chromosome, Human Artificial
- Human Artificial Chromosome
- HAC (Chromosome)
- Chromosomes, Human Artificial
- Human Artificial Chromosomes
|
Below are MeSH descriptors whose meaning is more general than "Chromosomes, Artificial, Human".
- Anatomy [A]
- Cells [A11]
- Cellular Structures [A11.284]
- Chromosomes [A11.284.187]
- Chromosomes, Artificial [A11.284.187.178]
- Chromosomes, Artificial, Mammalian [A11.284.187.178.190]
- Chromosomes, Artificial, Human [A11.284.187.178.190.117]
- Chromosomes, Mammalian [A11.284.187.520]
- Chromosomes, Artificial, Mammalian [A11.284.187.520.190]
- Chromosomes, Artificial, Human [A11.284.187.520.190.117]
- Chromosomes, Human [A11.284.187.520.300]
- Chromosomes, Artificial, Human [A11.284.187.520.300.117]
- Biological Sciences [G]
- Genetic Phenomena [G05]
- Genetic Structures [G05.360]
- Chromosomes [G05.360.162]
- Chromosomes, Artificial [G05.360.162.178]
- Chromosomes, Artificial, Mammalian [G05.360.162.178.190]
- Chromosomes, Artificial, Human [G05.360.162.178.190.117]
- Chromosomes, Mammalian [G05.360.162.520]
- Chromosomes, Artificial, Mammalian [G05.360.162.520.190]
- Chromosomes, Artificial, Human [G05.360.162.520.190.117]
- Chromosomes, Human [G05.360.162.520.300]
- Chromosomes, Artificial, Human [G05.360.162.520.300.117]
- Genetic Vectors [G05.360.337]
- Chromosomes, Artificial [G05.360.337.249]
- Chromosomes, Artificial, Mammalian [G05.360.337.249.190]
- Chromosomes, Artificial, Human [G05.360.337.249.190.117]
Below are MeSH descriptors whose meaning is more specific than "Chromosomes, Artificial, Human".
This graph shows the total number of publications written about "Chromosomes, Artificial, Human" by people in this website by year, and whether "Chromosomes, Artificial, Human" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Chromosomes, Artificial, Human" by people in Profiles.
-
Human artificial chromosome assembly by transposon-based retrofitting of genomic BACs with synthetic alpha-satellite arrays. Curr Protoc Hum Genet. 2007 Jan; Chapter 5:Unit 5.18.
-
Human artificial chromosomes: potential applications and clinical considerations. Pediatr Clin North Am. 2006 Oct; 53(5):843-53, viii.
-
Efficient assembly of de novo human artificial chromosomes from large genomic loci. BMC Biotechnol. 2005 Jul 05; 5:21.
-
Artificial and engineered chromosomes: non-integrating vectors for gene therapy. Trends Mol Med. 2005 May; 11(5):251-8.
-
Rapid creation of BAC-based human artificial chromosome vectors by transposition with synthetic alpha-satellite arrays. Nucleic Acids Res. 2005; 33(2):587-96.
-
Assembly and characterization of heterochromatin and euchromatin on human artificial chromosomes. Genome Biol. 2004; 5(11):R89.
-
Human artificial chromosomes with alpha satellite-based de novo centromeres show increased frequency of nondisjunction and anaphase lag. Mol Cell Biol. 2003 Nov; 23(21):7689-97.
-
Sequence organization and functional annotation of human centromeres. Cold Spring Harb Symp Quant Biol. 2003; 68:141-9.
-
Alpha-satellite DNA and vector composition influence rates of human artificial chromosome formation. Mol Ther. 2002 Jun; 5(6):798-805.
-
Genomic and genetic definition of a functional human centromere. Science. 2001 Oct 05; 294(5540):109-15.