"beta-Lactams" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Four-membered cyclic AMIDES, best known for the PENICILLINS based on a bicyclo-thiazolidine, as well as the CEPHALOSPORINS based on a bicyclo-thiazine, and including monocyclic MONOBACTAMS. The BETA-LACTAMASES hydrolyze the beta lactam ring, accounting for BETA-LACTAM RESISTANCE of infective bacteria.
| Descriptor ID |
D047090
|
| MeSH Number(s) |
D02.065.589.099 D02.886.108 D03.633.100.300
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "beta-Lactams".
Below are MeSH descriptors whose meaning is more specific than "beta-Lactams".
This graph shows the total number of publications written about "beta-Lactams" by people in this website by year, and whether "beta-Lactams" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 2 | 0 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "beta-Lactams" by people in Profiles.
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Time-resolved ?-lactam cleavage by L1 metallo-?-lactamase. Nat Commun. 2022 11 30; 13(1):7379.
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Prevalence and Characteristics of Non-Beta-Lactam Allergy Labeling at a Children's Hospital. J Pediatric Infect Dis Soc. 2021 05 28; 10(5):702.
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Investigating the impact of a ?-lactam allergy label on preoperative antibiotic prophylaxis administration. Infect Control Hosp Epidemiol. 2021 06; 42(6):710-714.
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The binding of antibiotics in OmpF porin. Structure. 2013 Jan 08; 21(1):76-87.
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Effect of body mass index on treatment of complicated intra-abdominal infections in hospitalized adults: comparison of ertapenem with piperacillin-tazobactam. Surg Infect (Larchmt). 2012 Feb; 13(1):38-42.
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Pseudomonas aeruginosa OspR is an oxidative stress sensing regulator that affects pigment production, antibiotic resistance and dissemination during infection. Mol Microbiol. 2010 Jan; 75(1):76-91.
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Accuracies of beta-lactam susceptibility test results for Pseudomonas aeruginosa with four automated systems (BD Phoenix, MicroScan WalkAway, Vitek, and Vitek 2). J Clin Microbiol. 2007 Apr; 45(4):1339-42.
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Glycopeptides are no more effective than beta-lactam agents for prevention of surgical site infection after cardiac surgery: a meta-analysis. Clin Infect Dis. 2004 May 15; 38(10):1357-63.
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Ertapenem once a day versus piperacillin-tazobactam every 6 hours for treatment of acute pelvic infections: a prospective, multicenter, randomized, double-blind study. Infect Dis Obstet Gynecol. 2003; 11(1):27-37.
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Protonation of the beta-lactam nitrogen is the trigger event in the catalytic action of class A beta-lactamases. Proc Natl Acad Sci U S A. 2000 Mar 28; 97(7):3160-5.