"Pyrrolizidine Alkaloids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of ALKALOIDS, characterized by a nitrogen-containing necine, occurring mainly in plants of the BORAGINACEAE; COMPOSITAE; and LEGUMINOSAE plant families. They can be activated in the liver by hydrolysis of the ester and desaturation of the necine base to reactive electrophilic pyrrolic CYTOTOXINS.
Descriptor ID |
D011763
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MeSH Number(s) |
D03.132.716 D03.633.100.772
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pyrrolizidine Alkaloids".
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Below are the most recent publications written about "Pyrrolizidine Alkaloids" by people in Profiles.
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Comparison of the hemodynamic effects of nitric oxide and endothelium-dependent vasodilators in intact lungs. J Appl Physiol (1985). 1990 Feb; 68(2):735-47.