 Shaker Superfamily of Potassium Channels
"Shaker Superfamily of Potassium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Voltage-gated potassium channels whose primary subunits contain six transmembrane segments and form tetramers to create a pore with a voltage sensor. They are related to their founding member, shaker protein, Drosophila.
| Descriptor ID |
D051637
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| MeSH Number(s) |
D12.776.157.530.400.600.900.500 D12.776.543.550.425.750.900.500 D12.776.543.585.400.750.900.624
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Shaker Superfamily of Potassium Channels".
Below are MeSH descriptors whose meaning is more specific than "Shaker Superfamily of Potassium Channels".
This graph shows the total number of publications written about "Shaker Superfamily of Potassium Channels" by people in this website by year, and whether "Shaker Superfamily of Potassium Channels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 1998 | 0 | 2 | 2 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 8 | 8 | | 2004 | 0 | 2 | 2 | | 2005 | 0 | 3 | 3 | | 2007 | 1 | 0 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 1 | 2 | | 2011 | 2 | 0 | 2 | | 2012 | 3 | 0 | 3 | | 2013 | 2 | 1 | 3 | | 2014 | 1 | 0 | 1 | | 2015 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 | | 2018 | 2 | 0 | 2 | | 2019 | 2 | 0 | 2 | | 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Shaker Superfamily of Potassium Channels" by people in Profiles.
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Priest MF, Lee EE, Bezanilla F. Tracking the movement of discrete gating charges in a voltage-gated potassium channel. Elife. 2021 11 15; 10.
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Bassetto CA, Carvalho-de-Souza JL, Bezanilla F. Molecular basis for functional connectivity between the voltage sensor and the selectivity filter gate in Shaker K+ channels. Elife. 2021 02 23; 10.
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Bassetto CAZ, Carvalho-de-Souza JL, Bezanilla F. Metal Bridge in S4 Segment Supports Helix Transition in Shaker Channel. Biophys J. 2020 02 25; 118(4):922-933.
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Carvalho-de-Souza JL, Bezanilla F. Noncanonical mechanism of voltage sensor coupling to pore revealed by tandem dimers of Shaker. Nat Commun. 2019 08 08; 10(1):3584.
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Infield DT, Lee EEL, Galpin JD, Galles GD, Bezanilla F, Ahern CA. Replacing voltage sensor arginines with citrulline provides mechanistic insight into charge versus shape. J Gen Physiol. 2018 07 02; 150(7):1017-1024.
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Carvalho-de-Souza JL, Bezanilla F. Nonsensing residues in S3-S4 linker's C terminus affect the voltage sensor set point in K+ channels. J Gen Physiol. 2018 02 05; 150(2):307-321.
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Martínez-Morales E, Kopljar I, Rainier JD, Tytgat J, Snyders DJ, Labro AJ. Gambierol and n-alkanols inhibit Shaker Kv channel via distinct binding sites outside the K(+) pore. Toxicon. 2016 Sep 15; 120:57-60.
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Martínez-Morales E, Kopljar I, Snyders DJ, Labro AJ. Alkanols inhibit voltage-gated K(+) channels via a distinct gating modifying mechanism that prevents gate opening. Sci Rep. 2015 Nov 30; 5:17402.
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Martinez-Morales E, Snyders DJ, Labro AJ. Mutations in the S6 gate isolate a late step in the activation pathway and reduce 4-AP sensitivity in shaker K(v) channel. Biophys J. 2014 Jan 07; 106(1):134-44.
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Priest MF, Lacroix JJ, Villalba-Galea CA, Bezanilla F. S3-S4 linker length modulates the relaxed state of a voltage-gated potassium channel. Biophys J. 2013 Nov 19; 105(10):2312-22.
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