"Kv1.5 Potassium Channel" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A delayed rectifier subtype of shaker potassium channels that conducts a delayed rectifier current. It contributes to ACTION POTENTIAL repolarization of MYOCYTES in HEART ATRIA.
| Descriptor ID |
D051666
|
| MeSH Number(s) |
D12.776.157.530.400.600.900.124.374 D12.776.157.530.400.600.900.500.241 D12.776.543.550.450.750.900.124.374 D12.776.543.550.450.750.900.500.241 D12.776.543.585.400.750.900.124.374 D12.776.543.585.400.750.900.624.241
|
| Concept/Terms |
Kv1.5 Potassium Channel- Kv1.5 Potassium Channel
- Potassium Channel, Kv1.5
- KCNA5 Potassium Channel
- Potassium Channel, KCNA5
|
Below are MeSH descriptors whose meaning is more general than "Kv1.5 Potassium Channel".
Below are MeSH descriptors whose meaning is more specific than "Kv1.5 Potassium Channel".
This graph shows the total number of publications written about "Kv1.5 Potassium Channel" by people in this website by year, and whether "Kv1.5 Potassium Channel" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 2 | 2 |
| 2005 | 1 | 1 | 2 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Kv1.5 Potassium Channel" by people in Profiles.
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A Kv channel with an altered activation gate sequence displays both "fast" and "slow" activation kinetics. Am J Physiol Cell Physiol. 2008 Jun; 294(6):C1476-84.
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Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1alpha-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer. Am J Physiol Heart Circ Physiol. 2008 Feb; 294(2):H570-8.
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The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted. Proc Natl Acad Sci U S A. 2007 Jul 03; 104(27):11418-23.
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Pergolide is an inhibitor of voltage-gated potassium channels, including Kv1.5, and causes pulmonary vasoconstriction. Circulation. 2005 Sep 06; 112(10):1494-9.
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Coupling of voltage sensing to channel opening reflects intrasubunit interactions in kv channels. J Gen Physiol. 2005 Jan; 125(1):71-80.
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Oxygen-sensitive Kv channel gene transfer confers oxygen responsiveness to preterm rabbit and remodeled human ductus arteriosus: implications for infants with patent ductus arteriosus. Circulation. 2004 Sep 14; 110(11):1372-9.
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Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells. Circ Res. 2004 Aug 06; 95(3):308-18.
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In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats. Circulation. 2003 Apr 22; 107(15):2037-44.
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PDGF upregulates delayed rectifier via Src family kinases and sphingosine kinase in oligodendroglial progenitors. Am J Physiol Cell Physiol. 2003 Jan; 284(1):C85-93.
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Impairment of hypoxic pulmonary vasoconstriction in mice lacking the voltage-gated potassium channel Kv1.5. FASEB J. 2001 Aug; 15(10):1801-3.