Ether-A-Go-Go Potassium Channels
"Ether-A-Go-Go Potassium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of voltage-gated potassium channels that are characterized by long N-terminal and C-terminal intracellular tails. They are named from the Drosophila protein whose mutation causes abnormal leg shaking under ether anesthesia. Their activation kinetics are dependent on extracellular MAGNESIUM and PROTON concentration.
| Descriptor ID |
D051638
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| MeSH Number(s) |
D12.776.157.530.400.600.900.249 D12.776.543.550.450.750.900.249 D12.776.543.585.400.750.900.249
|
| Concept/Terms |
Ether-A-Go-Go Potassium Channels- Ether-A-Go-Go Potassium Channels
- Ether A Go Go Potassium Channels
- Potassium Channels, Ether-A-Go-Go
- Eag-Related Potassium Channels
- Eag Related Potassium Channels
- Potassium Channels, Eag-Related
- Ether-A-Go-Go Related Potassium Channels
- Ether A Go Go Related Potassium Channels
- Eag Potassium Channels
- Potassium Channels, Eag
- ERG Potassium Channels
- Potassium Channels, ERG
|
Below are MeSH descriptors whose meaning is more general than "Ether-A-Go-Go Potassium Channels".
Below are MeSH descriptors whose meaning is more specific than "Ether-A-Go-Go Potassium Channels".
This graph shows the total number of publications written about "Ether-A-Go-Go Potassium Channels" by people in this website by year, and whether "Ether-A-Go-Go Potassium Channels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 2 | 0 | 2 |
| 2008 | 2 | 0 | 2 |
| 2009 | 2 | 0 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2013 | 0 | 1 | 1 |
| 2015 | 1 | 2 | 3 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ether-A-Go-Go Potassium Channels" by people in Profiles.
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Hypoxia induced hERG trafficking defect linked to cell cycle arrest in SH-SY5Y cells. PLoS One. 2019; 14(4):e0215905.
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Kv3.1 uses a timely resurgent K(+) current to secure action potential repolarization. Nat Commun. 2015 Dec 17; 6:10173.
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Calpain activation by ROS mediates human ether-a-go-go-related gene protein degradation by intermittent hypoxia. Am J Physiol Cell Physiol. 2016 Mar 01; 310(5):C329-36.
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QT interval prolongation in a patient with LQT2 on levetiracetam. Seizure. 2015 Jul; 29:134-6.
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Multi-parameter in vitro toxicity testing of crizotinib, sunitinib, erlotinib, and nilotinib in human cardiomyocytes. Toxicol Appl Pharmacol. 2013 Oct 01; 272(1):245-55.
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Molecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K+ channel inactivation pathway. J Biol Chem. 2011 Nov 11; 286(45):39091-9.
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Molecular microdomains in a sensory terminal, the vestibular calyx ending. J Neurosci. 2011 Jul 06; 31(27):10101-14.
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Phosphatidylinositol-4,5-bisphosphate (PIP(2)) stabilizes the open pore conformation of the Kv11.1 (hERG) channel. Biophys J. 2010 Aug 09; 99(4):1110-8.
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Hypoxia inhibits maturation and trafficking of hERG K(+) channel protein: Role of Hsp90 and ROS. Biochem Biophys Res Commun. 2009 Oct 16; 388(2):212-6.
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H(1) antihistamine drug promethazine directly blocks hERG K(+) channel. Pharmacol Res. 2009 Nov; 60(5):429-37.