Mitogen-Activated Protein Kinase 14
"Mitogen-Activated Protein Kinase 14" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 38-kDa mitogen-activated protein kinase that is abundantly expressed in a broad variety of cell types. It is involved in the regulation of cellular stress responses as well as the control of proliferation and survival of many cell types. The kinase activity of the enzyme is inhibited by the pyridinyl-imidazole compound SB 203580.
Descriptor ID |
D048308
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MeSH Number(s) |
D12.644.360.450.835.800
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Concept/Terms |
Mitogen-Activated Protein Kinase 14- Mitogen-Activated Protein Kinase 14
- Mitogen Activated Protein Kinase 14
- Cytokine Suppressive Anti-inflammatory Drug Binding Protein
- Cytokine Suppressive Anti inflammatory Drug Binding Protein
- Kinase CSBP
- CSBP, Kinase
- MAPK14
- MAPK14 Mitogen-Activated Protein Kinase
- MAPK14 Mitogen Activated Protein Kinase
- Stress-activated protein kinase 2a
- Stress activated protein kinase 2a
- Mxi2 Protein
- p38alpha MAP Kinase
- MAP Kinase, p38alpha
- p38alpha Mitogen-Activated Protein Kinase
- p38alpha Mitogen Activated Protein Kinase
- p38alphaMAPK
- SAPK2a
- CSAID-Binding Protein
- CSAID Binding Protein
- MAX-Interacting Protein 2
- MAX Interacting Protein 2
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Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinase 14".
Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinase 14".
This graph shows the total number of publications written about "Mitogen-Activated Protein Kinase 14" by people in this website by year, and whether "Mitogen-Activated Protein Kinase 14" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2009 | 1 | 0 | 1 | 2012 | 1 | 0 | 1 | 2013 | 0 | 1 | 1 | 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mitogen-Activated Protein Kinase 14" by people in Profiles.
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Namachivayam K, MohanKumar K, Arbach D, Jagadeeswaran R, Jain SK, Natarajan V, Mehta D, Jankov RP, Maheshwari A. All-Trans Retinoic Acid Induces TGF-ß2 in Intestinal Epithelial Cells via RhoA- and p38a MAPK-Mediated Activation of the Transcription Factor ATF2. PLoS One. 2015; 10(7):e0134003.
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Wissing ER, Boyer JG, Kwong JQ, Sargent MA, Karch J, McNally EM, Otsu K, Molkentin JD. P38a MAPK underlies muscular dystrophy and myofiber death through a Bax-dependent mechanism. Hum Mol Genet. 2014 Oct 15; 23(20):5452-63.
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Carbonetto P, Stephens M. Integrated enrichment analysis of variants and pathways in genome-wide association studies indicates central role for IL-2 signaling genes in type 1 diabetes, and cytokine signaling genes in Crohn's disease. PLoS Genet. 2013; 9(10):e1003770.
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Nishiki Y, Adewola A, Hatanaka M, Templin AT, Maier B, Mirmira RG. Translational control of inducible nitric oxide synthase by p38 MAPK in islet ß-cells. Mol Endocrinol. 2013 Feb; 27(2):336-49.
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Webber JL. Regulation of autophagy by p38alpha MAPK. Autophagy. 2010 Feb; 6(2):292-3.
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Webber JL, Tooze SA. Coordinated regulation of autophagy by p38alpha MAPK through mAtg9 and p38IP. EMBO J. 2010 Jan 06; 29(1):27-40.
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Dreixler JC, Barone FC, Shaikh AR, Du E, Roth S. Mitogen-activated protein kinase p38alpha and retinal ischemic preconditioning. Exp Eye Res. 2009 Nov; 89(5):782-90.
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Frey MR, Dise RS, Edelblum KL, Polk DB. p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration. EMBO J. 2006 Dec 13; 25(24):5683-92.
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