 MPTP Poisoning
"MPTP Poisoning" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A condition caused by the neurotoxin MPTP which causes selective destruction of nigrostriatal dopaminergic neurons. Clinical features include irreversible parkinsonian signs including rigidity and bradykinesia (PARKINSON DISEASE, SECONDARY). MPTP toxicity is also used as an animal model for the study of PARKINSON DISEASE. (Adams et al., Principles of Neurology, 6th ed, p1072; Neurology 1986 Feb;36(2):250-8)
| Descriptor ID |
D020267
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| MeSH Number(s) |
C10.228.140.079.862.800.300 C10.228.662.600.700.250 C10.720.606 C25.723.705.400
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| Concept/Terms |
MPTP Poisoning- MPTP Poisoning
- Poisoning, MPTP
- Poisoning, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
- Neurotoxicity Syndrome, MPTP
- MPTP Neurotoxicity Syndrome
- MPTP Neurotoxicity Syndromes
- Neurotoxicity Syndromes, MPTP
- MPTP-Induced Parkinsonism
- MPTP Induced Parkinsonism
- Parkinsonism, MPTP-Induced
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Below are MeSH descriptors whose meaning is more general than "MPTP Poisoning".
Below are MeSH descriptors whose meaning is more specific than "MPTP Poisoning".
This graph shows the total number of publications written about "MPTP Poisoning" by people in this website by year, and whether "MPTP Poisoning" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "MPTP Poisoning" by people in Profiles.
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Liu SM, Li XZ, Zhang SN, Yang ZM, Wang KX, Lu F, Wang CZ, Yuan CS. Acanthopanax senticosus Protects Structure and Function of Mesencephalic Mitochondria in A Mouse Model of Parkinson's Disease. Chin J Integr Med. 2018 Nov; 24(11):835-843.
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Petzinger GM, Fisher BE, McEwen S, Beeler JA, Walsh JP, Jakowec MW. Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease. Lancet Neurol. 2013 Jul; 12(7):716-26.
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Sen N, Hara MR, Ahmad AS, Cascio MB, Kamiya A, Ehmsen JT, Agrawal N, Aggrawal N, Hester L, Doré S, Snyder SH, Sawa A. GOSPEL: a neuroprotective protein that binds to GAPDH upon S-nitrosylation. Neuron. 2009 Jul 16; 63(1):81-91.
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