 Monocarboxylic Acid Transporters
"Monocarboxylic Acid Transporters" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of proteins involved in the transport of monocarboxylic acids such as LACTIC ACID and PYRUVIC ACID across cellular membranes.
| Descriptor ID |
D027501
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| MeSH Number(s) |
D12.776.157.530.450.074.500.400 D12.776.543.585.450.074.500.300
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| Concept/Terms |
Monocarboxylic Acid Transporters- Monocarboxylic Acid Transporters
- Acid Transporters, Monocarboxylic
- Transporters, Monocarboxylic Acid
- Monocarboxylate Translocator
- Translocator, Monocarboxylate
- Monocarboxylic Acid Transport Proteins
- MCT Proteins
- Monocarboxylic Acid Transport Protein
Erythrocyte Lactate Transporters- Erythrocyte Lactate Transporters
- Lactate Transporters, Erythrocyte
- Transporters, Erythrocyte Lactate
- Erythrocyte Lactate Transporter
- Lactate Transporter, Erythrocyte
- Transporter, Erythrocyte Lactate
Lactate Transport Proteins- Lactate Transport Proteins
- Transport Proteins, Lactate
- Lactate Transport Protein
- Transport Protein, Lactate
- Lactate Transporter
- Transporter, Lactate
- Lactate Translocase
- Translocase, Lactate
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Below are MeSH descriptors whose meaning is more general than "Monocarboxylic Acid Transporters".
Below are MeSH descriptors whose meaning is more specific than "Monocarboxylic Acid Transporters".
This graph shows the total number of publications written about "Monocarboxylic Acid Transporters" by people in this website by year, and whether "Monocarboxylic Acid Transporters" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 | | 2005 | 1 | 1 | 2 | | 2007 | 1 | 1 | 2 | | 2008 | 1 | 0 | 1 | | 2009 | 1 | 1 | 2 | | 2011 | 1 | 0 | 1 | | 2012 | 2 | 0 | 2 | | 2013 | 1 | 2 | 3 | | 2014 | 1 | 2 | 3 | | 2017 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Monocarboxylic Acid Transporters" by people in Profiles.
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Grijota-Martínez C, Bárez-López S, Ausó E, Refetoff S, Frey WH, Guadaño-Ferraz A. Intranasal delivery of Thyroid hormones in MCT8 deficiency. PLoS One. 2020; 15(7):e0236113.
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Bárez-López S, Grijota-Martínez C, Liao XH, Refetoff S, Guadaño-Ferraz A. Intracerebroventricular administration of the thyroid hormone analog TRIAC increases its brain content in the absence of MCT8. PLoS One. 2019; 14(12):e0226017.
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Vatine GD, Al-Ahmad A, Barriga BK, Svendsen S, Salim A, Garcia L, Garcia VJ, Ho R, Yucer N, Qian T, Lim RG, Wu J, Thompson LM, Spivia WR, Chen Z, Van Eyk J, Palecek SP, Refetoff S, Shusta EV, Svendsen CN. Modeling Psychomotor Retardation using iPSCs from MCT8-Deficient Patients Indicates a Prominent Role for the Blood-Brain Barrier. Cell Stem Cell. 2017 06 01; 20(6):831-843.e5.
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López-Espíndola D, Morales-Bastos C, Grijota-Martínez C, Liao XH, Lev D, Sugo E, Verge CF, Refetoff S, Bernal J, Guadaño-Ferraz A. Mutations of the thyroid hormone transporter MCT8 cause prenatal brain damage and persistent hypomyelination. J Clin Endocrinol Metab. 2014 Dec; 99(12):E2799-804.
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Chen C, Zhang C, Cheng L, Reilly JL, Bishop JR, Sweeney JA, Chen HY, Gershon ES, Liu C. Correlation between DNA methylation and gene expression in the brains of patients with bipolar disorder and schizophrenia. Bipolar Disord. 2014 Dec; 16(8):790-9.
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Núñez B, Martínez de Mena R, Obregon MJ, Font-Llitjós M, Nunes V, Palacín M, Dumitrescu AM, Morte B, Bernal J. Cerebral cortex hyperthyroidism of newborn mct8-deficient mice transiently suppressed by lat2 inactivation. PLoS One. 2014; 9(5):e96915.
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Fu J, Refetoff S, Dumitrescu AM. Inherited defects of thyroid hormone-cell-membrane transport: review of recent findings. Curr Opin Endocrinol Diabetes Obes. 2013 Oct; 20(5):434-40.
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Rodrigues TB, Ceballos A, Grijota-Martínez C, Nuñez B, Refetoff S, Cerdán S, Morte B, Bernal J. Increased oxidative metabolism and neurotransmitter cycling in the brain of mice lacking the thyroid hormone transporter SLC16A2 (MCT8). PLoS One. 2013; 8(10):e74621.
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Fu J, Dumitrescu AM. Inherited defects in thyroid hormone cell-membrane transport and metabolism. Best Pract Res Clin Endocrinol Metab. 2014 Mar; 28(2):189-201.
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Verge CF, Konrad D, Cohen M, Di Cosmo C, Dumitrescu AM, Marcinkowski T, Hameed S, Hamilton J, Weiss RE, Refetoff S. Diiodothyropropionic acid (DITPA) in the treatment of MCT8 deficiency. J Clin Endocrinol Metab. 2012 Dec; 97(12):4515-23.
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