Thyroid Hormone Receptors beta
"Thyroid Hormone Receptors beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRB gene (also known as NR1A2, THRB1, or ERBA2 gene) as several isoforms produced by alternative splicing. Mutations in the THRB gene cause THYROID HORMONE RESISTANCE SYNDROME.
| Descriptor ID |
D037042
|
| MeSH Number(s) |
D12.776.624.664.700.830.750 D12.776.826.850.750
|
| Concept/Terms |
Thyroid Hormone Receptors beta- Thyroid Hormone Receptors beta
- TR beta
- Thyroid Hormone Receptor beta
- ERBA2 Gene Products
- Gene Products, ERBA2
- NR1A2 Gene Products
- Gene Products, NR1A2
- Receptors beta, Thyroid Hormone
- c-erbA beta
- c erbA beta
- THRB Gene Products
- Gene Products, THRB
|
Below are MeSH descriptors whose meaning is more general than "Thyroid Hormone Receptors beta".
Below are MeSH descriptors whose meaning is more specific than "Thyroid Hormone Receptors beta".
This graph shows the total number of publications written about "Thyroid Hormone Receptors beta" by people in this website by year, and whether "Thyroid Hormone Receptors beta" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 2 | 2 |
| 2003 | 2 | 3 | 5 |
| 2004 | 1 | 3 | 4 |
| 2005 | 4 | 1 | 5 |
| 2006 | 2 | 1 | 3 |
| 2007 | 2 | 1 | 3 |
| 2008 | 2 | 1 | 3 |
| 2009 | 3 | 0 | 3 |
| 2010 | 4 | 0 | 4 |
| 2012 | 1 | 0 | 1 |
| 2013 | 3 | 0 | 3 |
| 2016 | 2 | 0 | 2 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 0 | 1 |
| 2019 | 3 | 0 | 3 |
| 2021 | 2 | 0 | 2 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thyroid Hormone Receptors beta" by people in Profiles.
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A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis. N Engl J Med. 2024 02 08; 390(6):497-509.
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Effect of the Fetal THRB Genotype on the Placenta. J Clin Endocrinol Metab. 2023 09 18; 108(10):e944-e948.
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The Relationship Between Fetal THRB Genotype and Maternal Thyroid Function. Thyroid. 2023 10; 33(10):1255-1258.
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Severe Resistance to Thyroid Hormone Beta in a Patient with Athyreosis. Thyroid. 2022 03; 32(3):336-339.
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Resistance to Thyroid Hormone Beta: A Focused Review. Front Endocrinol (Lausanne). 2021; 12:656551.
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Increased Hepatic Fat Content in Patients with Resistance to Thyroid Hormone Beta. Thyroid. 2021 07; 31(7):1127-1134.
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Very Severe Resistance to Thyroid Hormone ß in One of Three Affected Members of a Family with a Novel Mutation in the THRB Gene. Thyroid. 2019 10; 29(10):1518-1520.
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A Liver-Specific Thyromimetic, VK2809, Decreases Hepatosteatosis in Glycogen Storage Disease Type Ia. Thyroid. 2019 08; 29(8):1158-1167.
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Reduced Sensitivity to Thyroid Hormone as a Transgenerational Epigenetic Marker Transmitted Along the Human Male Line. Thyroid. 2019 06; 29(6):778-782.
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Human Genetics of Thyroid Hormone Receptor Beta: Resistance to Thyroid Hormone Beta (RTHß). Methods Mol Biol. 2018; 1801:225-240.