Cleavage And Polyadenylation Specificity Factor
"Cleavage And Polyadenylation Specificity Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An RNA-binding protein that recognizes the AAUAAA RNA SEQUENCE at the 3' end of MRNA. It contains four subunits of 30, 73, 100 and 160 kDa molecular size and combines with CLEAVAGE STIMULATION FACTOR to form a stable complex with mRNA that directs the 3' cleavage and polyadenylation reaction.
| Descriptor ID |
D039223
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| MeSH Number(s) |
D12.776.157.725.124.240 D12.776.664.962.444.240
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cleavage And Polyadenylation Specificity Factor".
Below are MeSH descriptors whose meaning is more specific than "Cleavage And Polyadenylation Specificity Factor".
This graph shows the total number of publications written about "Cleavage And Polyadenylation Specificity Factor" by people in this website by year, and whether "Cleavage And Polyadenylation Specificity Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cleavage And Polyadenylation Specificity Factor" by people in Profiles.
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Epidermal progenitors suppress GRHL3-mediated differentiation through intronic polyadenylation promoted by CPSF-HNRNPA3 collaboration. Nat Commun. 2021 01 19; 12(1):448.