"Sirtuin 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sirtuin family member found primarily in the CELL NUCLEUS. It is an NAD-dependent deacetylase with specificity towards HISTONES and a variety of proteins involved in gene regulation.
| Descriptor ID |
D056564
|
| MeSH Number(s) |
D08.811.277.087.520.200.650.100 D12.776.476.900.100
|
| Concept/Terms |
Sirtuin 1- Sirtuin 1
- Silent Mating Type Information Regulation 2 Homolog 1
|
Below are MeSH descriptors whose meaning is more general than "Sirtuin 1".
Below are MeSH descriptors whose meaning is more specific than "Sirtuin 1".
This graph shows the total number of publications written about "Sirtuin 1" by people in this website by year, and whether "Sirtuin 1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 3 | 0 | 3 |
| 2014 | 4 | 0 | 4 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 4 | 0 | 4 |
| 2019 | 3 | 1 | 4 |
| 2021 | 2 | 0 | 2 |
| 2022 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sirtuin 1" by people in Profiles.
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Amifostine ameliorates bleomycin-induced murine pulmonary fibrosis via NAD+/SIRT1/AMPK pathway-mediated effects on mitochondrial function and cellular metabolism. Eur J Med Res. 2024 Jan 20; 29(1):68.
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IGF2BP2 promotes cancer progression by degrading the RNA transcript encoding a v-ATPase subunit. Proc Natl Acad Sci U S A. 2022 Nov 08; 119(45):e2200477119.
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Chrysanthemum morifolium Flower Extract Ameliorates Obesity-Induced Inflammation and Increases the Muscle Mitochondria Content and AMPK/SIRT1 Activities in Obese Rats. Nutrients. 2021 Oct 19; 13(10).
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Pharmacological Advantage of SIRT2-Selective versus pan-SIRT1-3 Inhibitors. ACS Chem Biol. 2021 07 16; 16(7):1266-1275.
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Vitamin D Ameliorates Fat Accumulation with AMPK/SIRT1 Activity in C2C12 Skeletal Muscle Cells. Nutrients. 2019 Nov 17; 11(11).
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A Glycoconjugated SIRT2 Inhibitor with Aqueous Solubility Allows Structure-Based Design of SIRT2 Inhibitors. ACS Chem Biol. 2019 08 16; 14(8):1802-1810.
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Loss of Sirtuin 1 Alters the Secretome of Breast Cancer Cells by Impairing Lysosomal Integrity. Dev Cell. 2019 05 06; 49(3):393-408.e7.
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Tartary Buckwheat Extract Attenuated the Obesity-Induced Inflammation and Increased Muscle PGC-1a/SIRT1 Expression in High Fat Diet-Induced Obese Rats. Nutrients. 2019 Mar 18; 11(3).
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Epidermal SIRT1 regulates inflammation, cell migration, and wound healing. Sci Rep. 2017 10 26; 7(1):14110.
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Kallistatin reduces vascular senescence and aging by regulating microRNA-34a-SIRT1 pathway. Aging Cell. 2017 08; 16(4):837-846.