beta-Transducin Repeat-Containing Proteins
"beta-Transducin Repeat-Containing Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of F-box domain proteins that contain sequences that are homologous to the beta subunit of transducin (BETA-TRANSDUCIN). They play an important role in the protein degradation pathway by becoming components of SKP CULLIN F-BOX PROTEIN LIGASES, which selectively act on a subset of proteins including beta-catenin and IkappaBbeta.
Descriptor ID |
D044844
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MeSH Number(s) |
D12.776.157.169.500
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Concept/Terms |
beta-Transducin Repeat-Containing Proteins- beta-Transducin Repeat-Containing Proteins
- Repeat-Containing Proteins, beta-Transducin
- beta Transducin Repeat Containing Proteins
- beta-Transducin Repeat-Containing Protein
- Protein, beta-Transducin Repeat-Containing
- Repeat-Containing Protein, beta-Transducin
- beta Transducin Repeat Containing Protein
- beta-TrCP
- beta TrCP
- betaTrCP
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Below are MeSH descriptors whose meaning is more general than "beta-Transducin Repeat-Containing Proteins".
Below are MeSH descriptors whose meaning is more specific than "beta-Transducin Repeat-Containing Proteins".
This graph shows the total number of publications written about "beta-Transducin Repeat-Containing Proteins" by people in this website by year, and whether "beta-Transducin Repeat-Containing Proteins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2005 | 1 | 2 | 3 |
2006 | 1 | 0 | 1 |
2010 | 0 | 1 | 1 |
2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "beta-Transducin Repeat-Containing Proteins" by people in Profiles.
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De Novo Missense Variants in FBXW11 Cause Diverse Developmental Phenotypes Including Brain, Eye, and Digit Anomalies. Am J Hum Genet. 2019 09 05; 105(3):640-657.
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MicroRNA-10a regulation of proinflammatory phenotype in athero-susceptible endothelium in vivo and in vitro. Proc Natl Acad Sci U S A. 2010 Jul 27; 107(30):13450-5.
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Constitutive and UV-induced fibronectin degradation is a ubiquitination-dependent process controlled by beta-TrCP. J Biol Chem. 2006 Aug 11; 281(32):23060-5.
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The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate. Nat Cell Biol. 2005 Jul; 7(7):698-705.
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Wnt, hedgehog and snail: sister pathways that control by GSK-3beta and beta-Trcp in the regulation of metastasis. Cell Cycle. 2005 Jun; 4(6):772-6.
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Transforming growth factor beta facilitates beta-TrCP-mediated degradation of Cdc25A in a Smad3-dependent manner. Mol Cell Biol. 2005 Apr; 25(8):3338-47.