"Integrin alpha3beta1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface receptor for LAMININ, epiligrin, FIBRONECTINS, entactin, and COLLAGEN. Integrin alpha3beta1 is the major integrin present in EPITHELIAL CELLS, where it plays a role in the assembly of BASEMENT MEMBRANE as well as in cell migration, and may regulate the functions of other integrins. Two alternatively spliced isoforms of the alpha subunit (INTEGRIN ALPHA3), are differentially expressed in different cell types.
| Descriptor ID |
D039201
|
| MeSH Number(s) |
D12.776.543.750.685.300 D12.776.543.750.705.408.850.249 D12.776.543.750.705.876.311
|
| Concept/Terms |
Integrin alpha3beta1- Integrin alpha3beta1
- alpha3beta1, Integrin
- Gap b3
- VLA-3
- alpha3beta1 Epiligrin Receptor
- Epiligrin Receptor, alpha3beta1
- Receptor, alpha3beta1 Epiligrin
- Epiligrin Receptor
- Receptor, Epiligrin
- Galactoprotein b3
- Integrin alpha(3)beta(1)
- Laminin-5 Receptor (alpha3beta1 integrin)
- CD49c-CD29
- alpha3beta1 Integrin
- Integrin, alpha3beta1
|
Below are MeSH descriptors whose meaning is more general than "Integrin alpha3beta1".
Below are MeSH descriptors whose meaning is more specific than "Integrin alpha3beta1".
This graph shows the total number of publications written about "Integrin alpha3beta1" by people in this website by year, and whether "Integrin alpha3beta1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Integrin alpha3beta1" by people in Profiles.
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CD151-a3ß1 integrin complexes are prognostic markers of glioblastoma and cooperate with EGFR to drive tumor cell motility and invasion. Oncotarget. 2015 Oct 06; 6(30):29675-93.
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CD151-a3ß1 integrin complexes suppress ovarian tumor growth by repressing slug-mediated EMT and canonical Wnt signaling. Oncotarget. 2014 Dec 15; 5(23):12203-17.
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Laminin 511 partners with laminin 332 to mediate directional migration of Madin-Darby canine kidney epithelial cells. Mol Biol Cell. 2012 Jan; 23(1):121-36.
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Induction of a laminin isoform and alpha(3)beta(1)-integrin in renal ischemic injury and repair in vivo. Am J Physiol Renal Physiol. 2002 Nov; 283(5):F971-84.