 Glutamate Carboxypeptidase II
"Glutamate Carboxypeptidase II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A metallocarboxypeptidase that is predominantly expressed as a membrane-bound enzyme. It catalyzes the hydrolysis of an unsubstituted, C-terminal glutamyl residue, typically from PTEROYLPOLYGLUTAMIC ACIDS. It was formerly classified as EC 3.4.19.8.
| Descriptor ID |
D043425
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| MeSH Number(s) |
D08.811.277.656.350.245.400 D08.811.277.656.350.555.500 D08.811.277.656.675.555.500
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| Concept/Terms |
Glutamate Carboxypeptidase II- Glutamate Carboxypeptidase II
- Carboxypeptidase II, Glutamate
- FOLH1 Protein
- N-Acetylaspartylglutamate Peptidase
- N Acetylaspartylglutamate Peptidase
- Peptidase, N-Acetylaspartylglutamate
- NAALADase L
- NAAG Peptidase
- NAALADase
- NAALADase II
- Folate Hydrolase I
- Hydrolase I, Folate
- N-Acetylated-alpha-Linked Acidic Dipeptidase
- Acidic Dipeptidase, N-Acetylated-alpha-Linked
- Dipeptidase, N-Acetylated-alpha-Linked Acidic
- N Acetylated alpha Linked Acidic Dipeptidase
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Below are MeSH descriptors whose meaning is more general than "Glutamate Carboxypeptidase II".
Below are MeSH descriptors whose meaning is more specific than "Glutamate Carboxypeptidase II".
This graph shows the total number of publications written about "Glutamate Carboxypeptidase II" by people in this website by year, and whether "Glutamate Carboxypeptidase II" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2009 | 2 | 0 | 2 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glutamate Carboxypeptidase II" by people in Profiles.
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Walker LC, Marquart L, Pearson JF, Wiggins GA, O'Mara TA, Parsons MT. Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers. Eur J Hum Genet. 2017 04; 25(4):432-438.
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Thomas AG, Bodner A, Ghadge G, Roos RP, Slusher BS. GCP II inhibition rescues neurons from gp120IIIB-induced neurotoxicity. J Neurovirol. 2009 Sep; 15(5-6):449-57.
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Knight D, Peterson AC, Rini BI, Harlin H, Gajewski TF, Stadler WM. The HLA-A2-restricted PSMA peptide LLHETDSAV is poorly immunogenic in patients with metastatic prostate cancer. Prostate. 2009 Feb 01; 69(2):142-8.
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Ghadge GD, Slusher BS, Bodner A, Canto MD, Wozniak K, Thomas AG, Rojas C, Tsukamoto T, Majer P, Miller RJ, Monti AL, Roos RP. Glutamate carboxypeptidase II inhibition protects motor neurons from death in familial amyotrophic lateral sclerosis models. Proc Natl Acad Sci U S A. 2003 Aug 05; 100(16):9554-9.
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Rinker-Schaeffer CW, Hawkins AL, Su SL, Israeli RS, Griffin CA, Isaacs JT, Heston WD. Localization and physical mapping of the prostate-specific membrane antigen (PSM) gene to human chromosome 11. Genomics. 1995 Nov 01; 30(1):105-8.
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