"Carboxypeptidases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that act at a free C-terminus of a polypeptide to liberate a single amino acid residue.
| Descriptor ID |
D002268
|
| MeSH Number(s) |
D08.811.277.656.350.245
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Carboxypeptidases".
Below are MeSH descriptors whose meaning is more specific than "Carboxypeptidases".
This graph shows the total number of publications written about "Carboxypeptidases" by people in this website by year, and whether "Carboxypeptidases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 0 | 2 |
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Carboxypeptidases" by people in Profiles.
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Abrogation of immune complex glomerulonephritis by native carboxypeptidase and pharmacological antagonism of the C5a receptor. Cell Mol Immunol. 2016 09; 13(5):651-7.
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An aspartyl cathepsin, CTH3, is essential for proprotein processing during secretory granule maturation in Tetrahymena thermophila. Mol Biol Cell. 2014 Aug 15; 25(16):2444-60.
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Golgi maturation visualized in living yeast. Nature. 2006 Jun 22; 441(7096):1002-6.
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Glutamate carboxypeptidase II inhibition protects motor neurons from death in familial amyotrophic lateral sclerosis models. Proc Natl Acad Sci U S A. 2003 Aug 05; 100(16):9554-9.
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Proteolytic processing and Ca2+-binding activity of dense-core vesicle polypeptides in Tetrahymena. Mol Biol Cell. 1998 Feb; 9(2):497-511.
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Glucose-regulated translational control of proinsulin biosynthesis with that of the proinsulin endopeptidases PC2 and PC3 in the insulin-producing MIN6 cell line. Diabetes. 1996 Jan; 45(1):37-43.
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Increased secretory demand rather than a defect in the proinsulin conversion mechanism causes hyperproinsulinemia in a glucose-infusion rat model of non-insulin-dependent diabetes mellitus. J Clin Invest. 1995 Mar; 95(3):1032-9.
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Dominant chymotrypsin-like esterase activity in human lymphocyte granules is mediated by the serine carboxypeptidase called cathepsin A-like protective protein. J Immunol. 1994 Nov 15; 153(10):4663-72.
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Catalytic conformation of carboxypeptidase A. Structure of a true enzyme reaction intermediate determined by electron nuclear double resonance. J Biol Chem. 1994 Feb 11; 269(6):4587-95.
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Gut-specific genes from the black fly Simulium vittatum encoding trypsin-like and carboxypeptidase-like proteins. Insect Mol Biol. 1993; 1(3):149-63.