"Cytokine Receptor gp130" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine receptor that contains extracellular FIBRONECTIN TYPE III DOMAINS which mediate its function through the formation of oligomeric complexes with itself, or with a variety of CYTOKINE RECEPTORS. It does not bind IL-6, but activates JANUS KINASES and STAT3 TRANSCRIPTION FACTOR.
| Descriptor ID |
D050822
|
| MeSH Number(s) |
D12.776.543.750.705.852.420.400.500 D12.776.543.750.705.852.420.560.249 D12.776.543.750.705.852.555.600.500 D12.776.543.750.705.852.583.500 D12.776.543.750.750.400.550.250.500
|
| Concept/Terms |
Cytokine Receptor gp130- Cytokine Receptor gp130
- gp130, Cytokine Receptor
- IL-6 Receptor Signal Transducer gp130
- IL6ST gp130
- gp130 Transducing Protein
- Signal Transducer gp130
- gp130, Signal Transducer
- Antigens, CD130
- gp130 Signal Transducer
- Signal Transducer, gp130
- gp130 IL-6 Family Receptor
- gp130 IL 6 Family Receptor
- IL-6 Family Receptor gp130
- CD130 Antigens
- Interleukin-6 Receptor Subunit Beta
- Interleukin 6 Receptor Subunit Beta
- Signal-Transducing Receptor gp130
- Receptor gp130, Signal-Transducing
- Signal Transducing Receptor gp130
- gp130, Signal-Transducing Receptor
|
Below are MeSH descriptors whose meaning is more general than "Cytokine Receptor gp130".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Interleukin [D12.776.543.750.705.852.420]
- Receptors, Interleukin-6 [D12.776.543.750.705.852.420.400]
- Cytokine Receptor gp130 [D12.776.543.750.705.852.420.400.500]
- Receptors, Interleukin-11 [D12.776.543.750.705.852.420.560]
- Cytokine Receptor gp130 [D12.776.543.750.705.852.420.560.249]
- Receptors, Oncostatin M [D12.776.543.750.705.852.555]
- Receptors, Oncostatin M, Type II [D12.776.543.750.705.852.555.600]
- Cytokine Receptor gp130 [D12.776.543.750.705.852.555.600.500]
- Receptors, OSM-LIF [D12.776.543.750.705.852.583]
- Cytokine Receptor gp130 [D12.776.543.750.705.852.583.500]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Growth Factor [D12.776.543.750.750.400]
- Receptors, Nerve Growth Factor [D12.776.543.750.750.400.550]
- Receptor, Ciliary Neurotrophic Factor [D12.776.543.750.750.400.550.250]
- Cytokine Receptor gp130 [D12.776.543.750.750.400.550.250.500]
Below are MeSH descriptors whose meaning is more specific than "Cytokine Receptor gp130".
This graph shows the total number of publications written about "Cytokine Receptor gp130" by people in this website by year, and whether "Cytokine Receptor gp130" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Cytokine Receptor gp130" by people in Profiles.
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Macrophage-NLRP3 Activation Promotes Right Ventricle Failure in Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2022 09 01; 206(5):608-624.
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Inflammatory Glycoprotein 130 Signaling Links Changes in Microtubules and Junctophilin-2 to Altered Mitochondrial Metabolism and Right Ventricular Contractility. Circ Heart Fail. 2022 01; 15(1):e008574.
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Metabolically activated adipose tissue macrophages link obesity to triple-negative breast cancer. J Exp Med. 2019 06 03; 216(6):1345-1358.
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Essential role of neutrophil mobilization in concanavalin A-induced hepatitis is based on classic IL-6 signaling but not on IL-6 trans-signaling. Biochim Biophys Acta. 2011 Mar; 1812(3):290-301.
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A role for IL-27p28 as an antagonist of gp130-mediated signaling. Nat Immunol. 2010 Dec; 11(12):1119-26.
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Role of IL-6 trans-signaling in CCl4induced liver damage. Biochim Biophys Acta. 2010 Nov; 1802(11):1054-61.
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Impact of interleukin-6 classic- and trans-signaling on liver damage and regeneration. J Autoimmun. 2010 Feb; 34(1):29-37.
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The development and compensation of biliary cirrhosis in interleukin-6-deficient mice. Am J Pathol. 2000 May; 156(5):1627-39.