GATA1 Transcription Factor
"GATA1 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A GATA transcription factor that is specifically expressed in hematopoietic lineages and plays an important role in the CELL DIFFERENTIATION of ERYTHROID CELLS and MEGAKARYOCYTES.
Descriptor ID |
D050982
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MeSH Number(s) |
D12.776.260.235.500 D12.776.260.257.100 D12.776.930.316.500 D12.776.930.321.100
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Concept/Terms |
GATA1 Transcription Factor- GATA1 Transcription Factor
- Transcription Factor, GATA1
- Erythroid Transcription Factor 1
- Transcription Factor NFE-1
- NFE-1, Transcription Factor
- NF-E1 Erythroid-Specific Transcription Factor
- NF E1 Erythroid Specific Transcription Factor
- Nuclear Factor-Erythroid 1
- Nuclear Factor Erythroid 1
- Transcription Factor GATA1
- Factor GATA1, Transcription
- GATA1, Transcription Factor
- Eryf1 Erythroid-Specific Transcription Factor
- Eryf1 Erythroid Specific Transcription Factor
- Globin Transcription Factor 1
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Below are MeSH descriptors whose meaning is more general than "GATA1 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "GATA1 Transcription Factor".
This graph shows the total number of publications written about "GATA1 Transcription Factor" by people in this website by year, and whether "GATA1 Transcription Factor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 3 | 3 | 2007 | 1 | 0 | 1 | 2010 | 0 | 3 | 3 | 2012 | 1 | 3 | 4 | 2013 | 0 | 1 | 1 | 2017 | 1 | 0 | 1 | 2018 | 0 | 2 | 2 |
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Below are the most recent publications written about "GATA1 Transcription Factor" by people in Profiles.
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Manso BA, Zhang H, Mikkelson MG, Gwin KA, Secreto CR, Ding W, Parikh SA, Kay NE, Medina KL. Bone marrow hematopoietic dysfunction in untreated chronic lymphocytic leukemia patients. Leukemia. 2019 03; 33(3):638-652.
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Cheng JX, Chen L, Li Y, Cloe A, Yue M, Wei J, Watanabe KA, Shammo JM, Anastasi J, Shen QJ, Larson RA, He C, Le Beau MM, Vardiman JW. RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia. Nat Commun. 2018 03 21; 9(1):1163.
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Gilles L, Arslan AD, Marinaccio C, Wen QJ, Arya P, McNulty M, Yang Q, Zhao JC, Konstantinoff K, Lasho T, Pardanani A, Stein B, Plo I, Sundaravel S, Wickrema A, Migliaccio A, Gurbuxani S, Vainchenker W, Platanias LC, Tefferi A, Crispino JD. Downregulation of GATA1 drives impaired hematopoiesis in primary myelofibrosis. J Clin Invest. 2017 Apr 03; 127(4):1316-1320.
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Zhou Y, Kurukuti S, Saffrey P, Vukovic M, Michie AM, Strogantsev R, West AG, Vetrie D. Chromatin looping defines expression of TAL1, its flanking genes, and regulation in T-ALL. Blood. 2013 Dec 19; 122(26):4199-209.
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Zhu X, Wang Y, Pi W, Liu H, Wickrema A, Tuan D. NF-Y recruits both transcription activator and repressor to modulate tissue- and developmental stage-specific expression of human ?-globin gene. PLoS One. 2012; 7(10):e47175.
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Ganis JJ, Hsia N, Trompouki E, de Jong JL, DiBiase A, Lambert JS, Jia Z, Sabo PJ, Weaver M, Sandstrom R, Stamatoyannopoulos JA, Zhou Y, Zon LI. Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR. Dev Biol. 2012 Jun 15; 366(2):185-94.
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Doré LC, Chlon TM, Brown CD, White KP, Crispino JD. Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis. Blood. 2012 Apr 19; 119(16):3724-33.
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Malinge S, Bliss-Moreau M, Kirsammer G, Diebold L, Chlon T, Gurbuxani S, Crispino JD. Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome. J Clin Invest. 2012 Mar; 122(3):948-62.
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Figueroa ME, Abdel-Wahab O, Lu C, Ward PS, Patel J, Shih A, Li Y, Bhagwat N, Vasanthakumar A, Fernandez HF, Tallman MS, Sun Z, Wolniak K, Peeters JK, Liu W, Choe SE, Fantin VR, Paietta E, Löwenberg B, Licht JD, Godley LA, Delwel R, Valk PJ, Thompson CB, Levine RL, Melnick A. Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell. 2010 Dec 14; 18(6):553-67.
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Small S, Keerthivasan G, Huang Z, Gurbuxani S, Crispino JD. Overexpression of survivin initiates hematologic malignancies in vivo. Leukemia. 2010 Nov; 24(11):1920-6.
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