GATA1 Transcription Factor
"GATA1 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A GATA transcription factor that is specifically expressed in hematopoietic lineages and plays an important role in the CELL DIFFERENTIATION of ERYTHROID CELLS and MEGAKARYOCYTES.
| Descriptor ID |
D050982
|
| MeSH Number(s) |
D12.776.260.235.500 D12.776.260.257.100 D12.776.930.216.500 D12.776.930.314.100
|
| Concept/Terms |
GATA1 Transcription Factor- GATA1 Transcription Factor
- Transcription Factor, GATA1
- NF-E1 Erythroid-Specific Transcription Factor
- NF E1 Erythroid Specific Transcription Factor
- Transcription Factor NFE-1
- NFE-1, Transcription Factor
- Transcription Factor GATA1
- Factor GATA1, Transcription
- GATA1, Transcription Factor
- Globin Transcription Factor 1
- Nuclear Factor-Erythroid 1
- Nuclear Factor Erythroid 1
- Eryf1 Erythroid-Specific Transcription Factor
- Eryf1 Erythroid Specific Transcription Factor
- Erythroid Transcription Factor 1
|
Below are MeSH descriptors whose meaning is more general than "GATA1 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "GATA1 Transcription Factor".
This graph shows the total number of publications written about "GATA1 Transcription Factor" by people in this website by year, and whether "GATA1 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 3 | 3 |
| 2007 | 1 | 0 | 1 |
| 2010 | 0 | 3 | 3 |
| 2012 | 1 | 3 | 4 |
| 2013 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 2 | 2 |
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Below are the most recent publications written about "GATA1 Transcription Factor" by people in Profiles.
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Bone marrow hematopoietic dysfunction in untreated chronic lymphocytic leukemia patients. Leukemia. 2019 03; 33(3):638-652.
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RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia. Nat Commun. 2018 03 21; 9(1):1163.
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Downregulation of GATA1 drives impaired hematopoiesis in primary myelofibrosis. J Clin Invest. 2017 Apr 03; 127(4):1316-1320.
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Chromatin looping defines expression of TAL1, its flanking genes, and regulation in T-ALL. Blood. 2013 Dec 19; 122(26):4199-209.
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NF-Y recruits both transcription activator and repressor to modulate tissue- and developmental stage-specific expression of human ?-globin gene. PLoS One. 2012; 7(10):e47175.
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Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR. Dev Biol. 2012 Jun 15; 366(2):185-94.
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Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis. Blood. 2012 Apr 19; 119(16):3724-33.
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Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome. J Clin Invest. 2012 Mar; 122(3):948-62.
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Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell. 2010 Dec 14; 18(6):553-67.
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Overexpression of survivin initiates hematologic malignancies in vivo. Leukemia. 2010 Nov; 24(11):1920-6.