Frontotemporal Lobar Degeneration
"Frontotemporal Lobar Degeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Heterogeneous group of neurodegenerative disorders characterized by frontal and temporal lobe atrophy associated with neuronal loss, gliosis, and dementia. Patients exhibit progressive changes in social, behavioral, and/or language function. Multiple subtypes or forms are recognized based on presence or absence of TAU PROTEIN inclusions. FTLD includes three clinical syndromes: FRONTOTEMPORAL DEMENTIA, semantic dementia, and PRIMARY PROGRESSIVE NONFLUENT APHASIA.
| Descriptor ID |
D057174
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| MeSH Number(s) |
C10.228.140.380.266 C10.574.950.300 C18.452.845.800.300 F03.615.400.380
|
| Concept/Terms |
Frontotemporal Lobar Degeneration- Frontotemporal Lobar Degeneration
- Degeneration, Frontotemporal Lobar
- Degenerations, Frontotemporal Lobar
- Frontotemporal Lobar Degenerations
- Lobar Degeneration, Frontotemporal
- Lobar Degenerations, Frontotemporal
- FTLD
- FTLDs
|
Below are MeSH descriptors whose meaning is more general than "Frontotemporal Lobar Degeneration".
Below are MeSH descriptors whose meaning is more specific than "Frontotemporal Lobar Degeneration".
This graph shows the total number of publications written about "Frontotemporal Lobar Degeneration" by people in this website by year, and whether "Frontotemporal Lobar Degeneration" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2014 | 2 | 0 | 2 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 2 | 0 | 2 |
| 2020 | 3 | 0 | 3 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Frontotemporal Lobar Degeneration" by people in Profiles.
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Phenotypically concordant distribution of pick bodies in aphasic versus behavioral dementias. Acta Neuropathol Commun. 2024 Feb 22; 12(1):31.
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Frontotemporal Degeneration with Transactive Response DNA-Binding Protein Type C at the Anterior Temporal Lobe. Ann Neurol. 2023 07; 94(1):1-12.
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Cortical and subcortical pathological burden and neuronal loss in an autopsy series of FTLD-TDP-type C. Brain. 2022 04 29; 145(3):1069-1078.
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Nosology of Primary Progressive Aphasia and the Neuropathology of Language. Adv Exp Med Biol. 2021; 1281:33-49.
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Speech and Language Presentations of FTLD-TDP Type B Neuropathology. J Neuropathol Exp Neurol. 2020 03 01; 79(3):277-283.
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Clinical and volumetric changes with increasing functional impairment in familial frontotemporal lobar degeneration. Alzheimers Dement. 2020 01; 16(1):49-59.
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Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium. Alzheimers Dement. 2020 01; 16(1):106-117.
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FTLD-TDP With and Without GRN Mutations Cause Different Patterns of CA1 Pathology. J Neuropathol Exp Neurol. 2019 09 01; 78(9):844-853.
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Revisiting the utility of TDP-43 immunoreactive (TDP-43-ir) pathology to classify FTLD-TDP subtypes. Acta Neuropathol. 2019 07; 138(1):167-169.
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Atrophy and microglial distribution in primary progressive aphasia with transactive response DNA-binding protein-43 kDa. Ann Neurol. 2018 06; 83(6):1096-1104.