"Lewy Body Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)
| Descriptor ID |
D020961
|
| MeSH Number(s) |
C10.228.140.079.862.400 C10.228.140.380.422 C10.228.662.600.200 C10.574.531 F03.615.400.512
|
| Concept/Terms |
Lewy Body Disease- Lewy Body Disease
- Diffuse Lewy Body Disease
- Lewy Body Dementia
- Cortical Lewy Body Disease
- Lewy Body Disease, Cortical
- Lewy Body Type Senile Dementia
- Lewy Body Disease, Diffuse
- Dementia, Lewy Body
|
Below are MeSH descriptors whose meaning is more general than "Lewy Body Disease".
Below are MeSH descriptors whose meaning is more specific than "Lewy Body Disease".
This graph shows the total number of publications written about "Lewy Body Disease" by people in this website by year, and whether "Lewy Body Disease" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 2 | 0 | 2 |
| 2007 | 1 | 1 | 2 |
| 2010 | 2 | 0 | 2 |
| 2014 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lewy Body Disease" by people in Profiles.
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Evaluation of N- and O-Linked Indole Triazines for a Dual Effect on a-Synuclein and Tau Aggregation. ACS Chem Neurosci. 2023 11 01; 14(21):3913-3927.
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Foreword for Recent Advances in Alzheimer...s and Lewy Body Dementia: A comprehensive review. Dis Mon. 2023 May; 69(5):101440.
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MAPT haplotype H1G is associated with increased risk of dementia with Lewy bodies. Alzheimers Dement. 2016 Dec; 12(12):1297-1304.
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Role for the microtubule-associated protein tau variant p.A152T in risk of a-synucleinopathies. Neurology. 2015 Nov 10; 85(19):1680-6.
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Cholinergic symptoms with low serum cholinesterase from therapeutic cholinesterase inhibitor toxicity. Am J Emerg Med. 2014 Jul; 32(7):815.e3-4.
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Widespread distribution of reticulon-3 in various neurodegenerative diseases. Neuropathology. 2010 Dec; 30(6):574-9.
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CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson's disease. J Neural Transm (Vienna). 2011 Jan; 118(1):23-6.
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Comparison of risk factor profiles in incidental Lewy body disease and Parkinson disease. Arch Neurol. 2009 Sep; 66(9):1114-9.
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Incidental Lewy body disease: do some cases represent a preclinical stage of dementia with Lewy bodies? Neurobiol Aging. 2011 May; 32(5):857-63.
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Enhanced accumulation of phosphorylated alpha-synuclein and elevated beta-amyloid 42/40 ratio caused by expression of the presenilin-1 deltaT440 mutant associated with familial Lewy body disease and variant Alzheimer's disease. J Neurosci. 2007 Nov 28; 27(48):13092-7.