 Ursodeoxycholic Acid
"Ursodeoxycholic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An epimer of chenodeoxycholic acid. It is a mammalian bile acid found first in the bear and is apparently either a precursor or a product of chenodeoxycholate. Its administration changes the composition of bile and may dissolve gallstones. It is used as a cholagogue and choleretic.
| Descriptor ID |
D014580
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| MeSH Number(s) |
D04.808.105.225.272.962 D04.808.221.430.342.925
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| Concept/Terms |
Ursodeoxycholic Acid- Ursodeoxycholic Acid
- Acid, Ursodeoxycholic
- Ursacholic Acid
- Acid, Ursacholic
- 3 alpha,7 beta-Dihydroxy-5 beta-cholan-24-oic Acid
- 3 alpha,7 beta Dihydroxy 5 beta cholan 24 oic Acid
- Ursodiol
- Deoxyursocholic Acid
- Acid, Deoxyursocholic
Ursobilane- Ursobilane
- Estedi Brand of Ursodeoxycholic Acid
Ursogal- Ursogal
- Galen Brand of Ursodeoxycholic Acid
Ursolite- Ursolite
- Vita Brand of Ursodeoxycholic Acid
Ursolvan- Ursolvan
- Sanofi Synthelabo Brand of Ursodeoxycholic Acid
Cholofalk- Cholofalk
- Falk Brand of Ursodeoxycholic Acid
Cholit-Ursan- Cholit-Ursan
- Niddapharm Brand of Ursodeoxycholic Acid
Urso Heumann- Urso Heumann
- Heumann Brand of Ursodeoxycholic Acid
Delursan- Delursan
- Aventis Brand of Ursodeoxycholic Acid
Destolit- Destolit
- Norgine Brand of Ursodeoxycholic Acid
Urdox- Urdox
- CP Brand of Ursodeoxycholic Acid
Urso- Urso
- Axcan Brand of Ursodeoxycholic Acid
Ursochol- Ursochol
- Zambon Brand of Ursodeoxycholic Acid
Ursofalk- Ursofalk
- Tramedico Brand of Ursodeoxycholic Acid
- Orphan Brand of Ursodeoxycholic Acid
- Provalis Brand of Ursodeoxycholic Acid
- Antigen Brand of Ursodeoxycholic Acid
- Farmasa Brand of Ursodeoxycholic Acid
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Below are MeSH descriptors whose meaning is more general than "Ursodeoxycholic Acid".
Below are MeSH descriptors whose meaning is more specific than "Ursodeoxycholic Acid".
This graph shows the total number of publications written about "Ursodeoxycholic Acid" by people in this website by year, and whether "Ursodeoxycholic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 1 | 2 | | 1995 | 1 | 0 | 1 | | 1997 | 1 | 0 | 1 | | 2002 | 2 | 0 | 2 | | 2003 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2014 | 0 | 2 | 2 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ursodeoxycholic Acid" by people in Profiles.
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Mataya L, Patel N, Azzam RK. Autoimmune Liver Diseases in Children. Pediatr Ann. 2018 Nov 01; 47(11):e452-e457.
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Paul S, Sepehr GJ, Weinstein B, Roper J. Co-occurrence of idiopathic granulomatous hepatitis and primary biliary cirrhosis. Dig Dis Sci. 2014 Nov; 59(11):2831-5.
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Chapman CG, Rubin DT. The potential for medical therapy to reduce the risk of colorectal cancer and optimize surveillance in inflammatory bowel disease. Gastrointest Endosc Clin N Am. 2014 Jul; 24(3):353-65.
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Rocha MS, Herbella FA, Del Grande JC, Ferreira AT, Tahan C, Patti MG. Effects of ursodeoxycholic acid in esophageal motility and the role of the mucosa. An experimental study. Dis Esophagus. 2011 May; 24(4):291-4.
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Serfaty L, Bissonnette M, Poupon R. Ursodeoxycholic acid and chemoprevention of colorectal cancer. Gastroenterol Clin Biol. 2010 Oct; 34(10):516-22.
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Khare S, Mustafi R, Cerda S, Yuan W, Jagadeeswaran S, Dougherty U, Tretiakova M, Samarel A, Cohen G, Wang J, Moore C, Wali R, Holgren C, Joseph L, Fichera A, Li YC, Bissonnette M. Ursodeoxycholic acid suppresses Cox-2 expression in colon cancer: roles of Ras, p38, and CCAAT/enhancer-binding protein. Nutr Cancer. 2008; 60(3):389-400.
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Wolf JM, Rybicki LA, Lashner BA. The impact of ursodeoxycholic acid on cancer, dysplasia and mortality in ulcerative colitis patients with primary sclerosing cholangitis. Aliment Pharmacol Ther. 2005 Nov 01; 22(9):783-8.
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Khare S, Cerda S, Wali RK, von Lintig FC, Tretiakova M, Joseph L, Stoiber D, Cohen G, Nimmagadda K, Hart J, Sitrin MD, Boss GR, Bissonnette M. Ursodeoxycholic acid inhibits Ras mutations, wild-type Ras activation, and cyclooxygenase-2 expression in colon cancer. Cancer Res. 2003 Jul 01; 63(13):3517-23.
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Wali RK, Khare S, Tretiakova M, Cohen G, Nguyen L, Hart J, Wang J, Wen M, Ramaswamy A, Joseph L, Sitrin M, Brasitus T, Bissonnette M. Ursodeoxycholic acid and F(6)-D(3) inhibit aberrant crypt proliferation in the rat azoxymethane model of colon cancer: roles of cyclin D1 and E-cadherin. Cancer Epidemiol Biomarkers Prev. 2002 Dec; 11(12):1653-62.
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Wali RK, Stoiber D, Nguyen L, Hart J, Sitrin MD, Brasitus T, Bissonnette M. Ursodeoxycholic acid inhibits the initiation and postinitiation phases of azoxymethane-induced colonic tumor development. Cancer Epidemiol Biomarkers Prev. 2002 Nov; 11(11):1316-21.
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